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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALKBH8
All Species:
19.39
Human Site:
S536
Identified Species:
35.56
UniProt:
Q96BT7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BT7
NP_620130.2
664
75208
S536
E
E
M
N
S
D
T
S
V
Q
R
S
L
V
E
Chimpanzee
Pan troglodytes
XP_522172
664
75155
S536
E
E
M
N
S
D
T
S
V
Q
R
S
L
V
E
Rhesus Macaque
Macaca mulatta
XP_001102763
664
75113
S536
E
E
M
N
S
D
T
S
V
Q
R
S
L
V
E
Dog
Lupus familis
XP_546542
661
74257
A536
E
G
T
S
S
D
T
A
M
P
E
L
L
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y20
664
74749
S536
D
E
L
N
S
A
T
S
T
E
E
F
L
V
N
Rat
Rattus norvegicus
XP_001055538
664
74826
S536
G
E
L
N
S
A
T
S
M
E
Q
L
L
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508849
715
79108
G587
G
E
E
E
Q
S
N
G
E
A
E
L
L
G
E
Chicken
Gallus gallus
XP_417166
679
76991
T547
E
E
E
S
S
T
G
T
S
Q
R
L
L
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684243
693
77051
E560
G
G
E
E
L
K
T
E
E
N
K
A
I
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611690
615
69276
S504
Q
R
K
N
D
K
K
S
T
Y
L
R
Q
N
K
Honey Bee
Apis mellifera
XP_395117
558
65352
V447
N
G
K
C
L
I
Y
V
W
A
K
E
Q
E
K
Nematode Worm
Caenorhab. elegans
NP_497751
591
67352
G480
L
L
R
V
V
K
P
G
S
K
I
C
V
T
V
Sea Urchin
Strong. purpuratus
XP_797576
424
47124
P313
V
I
P
D
P
T
F
P
D
N
L
T
L
H
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
96.9
82.6
N.A.
77.2
76.8
N.A.
66.4
66.2
N.A.
55.5
N.A.
42.3
40.9
35.6
32.9
Protein Similarity:
100
99
98.4
90.3
N.A.
85.5
84.9
N.A.
77.6
80.8
N.A.
71
N.A.
57.6
57.2
54.2
45.1
P-Site Identity:
100
100
100
46.6
N.A.
46.6
46.6
N.A.
20
40
N.A.
6.6
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
73.3
N.A.
20
60
N.A.
33.3
N.A.
26.6
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
8
0
16
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
8
8
31
0
0
8
0
0
0
0
8
8
% D
% Glu:
39
54
24
16
0
0
0
8
16
16
24
8
0
8
39
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
24
24
0
0
0
0
8
16
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
16
0
0
24
8
0
0
8
16
0
0
0
24
% K
% Leu:
8
8
16
0
16
0
0
0
0
0
16
31
70
0
0
% L
% Met:
0
0
24
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
8
0
0
47
0
0
8
0
0
16
0
0
0
8
16
% N
% Pro:
0
0
8
0
8
0
8
8
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
31
8
0
16
8
8
% Q
% Arg:
0
8
8
0
0
0
0
0
0
0
31
8
0
0
0
% R
% Ser:
0
0
0
16
54
8
0
47
16
0
0
24
0
0
0
% S
% Thr:
0
0
8
0
0
16
54
8
16
0
0
8
0
8
0
% T
% Val:
8
0
0
8
8
0
0
8
24
0
0
0
8
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _