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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALKBH8 All Species: 13.64
Human Site: S553 Identified Species: 25
UniProt: Q96BT7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BT7 NP_620130.2 664 75208 S553 R D M G S R D S A S S V P R I
Chimpanzee Pan troglodytes XP_522172 664 75155 S553 P D M G S Q D S P F S V P R I
Rhesus Macaque Macaca mulatta XP_001102763 664 75113 S553 P D M G S R D S A S S V P R I
Dog Lupus familis XP_546542 661 74257 S553 P N V G S R D S E C C V S S V
Cat Felis silvestris
Mouse Mus musculus Q80Y20 664 74749 P553 P E G V N E D P A L S V N S S
Rat Rattus norvegicus XP_001055538 664 74826 P553 P E G V S E D P G L S V H S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508849 715 79108 A604 P D S G G P E A V R S V P P A
Chicken Gallus gallus XP_417166 679 76991 S564 H D R S S Q G S A C S D R L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684243 693 77051 D577 H D R N M I S D I R C T D D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611690 615 69276 Q521 N K E R T T E Q Q Q R Q K Q H
Honey Bee Apis mellifera XP_395117 558 65352 Y464 I Q T A Y L R Y N L I K K E D
Nematode Worm Caenorhab. elegans NP_497751 591 67352 Y497 M D Q S Q S E Y A K M R G N K
Sea Urchin Strong. purpuratus XP_797576 424 47124 R330 Q R T S F T F R A V R G G P C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 96.9 82.6 N.A. 77.2 76.8 N.A. 66.4 66.2 N.A. 55.5 N.A. 42.3 40.9 35.6 32.9
Protein Similarity: 100 99 98.4 90.3 N.A. 85.5 84.9 N.A. 77.6 80.8 N.A. 71 N.A. 57.6 57.2 54.2 45.1
P-Site Identity: 100 73.3 93.3 40 N.A. 26.6 26.6 N.A. 33.3 33.3 N.A. 6.6 N.A. 0 0 13.3 6.6
P-Site Similarity: 100 80 93.3 60 N.A. 40 33.3 N.A. 46.6 46.6 N.A. 6.6 N.A. 20 0 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 47 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 16 16 0 0 0 8 % C
% Asp: 0 54 0 0 0 0 47 8 0 0 0 8 8 8 8 % D
% Glu: 0 16 8 0 0 16 24 0 8 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 16 39 8 0 8 0 8 0 0 8 16 0 8 % G
% His: 16 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 8 0 0 0 0 8 0 0 8 0 8 0 0 0 24 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 0 8 16 0 8 % K
% Leu: 0 0 0 0 0 8 0 0 0 24 0 0 0 8 8 % L
% Met: 8 0 24 0 8 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 8 0 8 8 0 0 0 8 0 0 0 8 8 0 % N
% Pro: 47 0 0 0 0 8 0 16 8 0 0 0 31 16 0 % P
% Gln: 8 8 8 0 8 16 0 8 8 8 0 8 0 8 0 % Q
% Arg: 8 8 16 8 0 24 8 8 0 16 16 8 8 24 0 % R
% Ser: 0 0 8 24 47 8 8 39 0 16 54 0 8 24 16 % S
% Thr: 0 0 16 0 8 16 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 8 16 0 0 0 0 8 8 0 54 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _