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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALKBH8
All Species:
23.64
Human Site:
Y216
Identified Species:
43.33
UniProt:
Q96BT7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BT7
NP_620130.2
664
75208
Y216
E
K
W
L
R
K
G
Y
I
K
H
K
P
D
Q
Chimpanzee
Pan troglodytes
XP_522172
664
75155
Y216
E
K
W
L
R
E
G
Y
I
K
H
K
P
D
Q
Rhesus Macaque
Macaca mulatta
XP_001102763
664
75113
Y216
E
K
W
L
R
E
G
Y
I
K
H
K
P
D
Q
Dog
Lupus familis
XP_546542
661
74257
F216
E
K
W
L
K
E
G
F
I
K
H
K
P
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y20
664
74749
Y216
E
K
L
L
K
E
G
Y
I
K
H
K
P
D
Q
Rat
Rattus norvegicus
XP_001055538
664
74826
Y216
E
K
L
L
K
E
G
Y
I
K
H
K
P
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508849
715
79108
H267
E
R
C
L
K
Q
G
H
I
K
I
S
P
D
Q
Chicken
Gallus gallus
XP_417166
679
76991
Y224
E
K
C
L
K
Q
G
Y
I
K
H
K
P
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684243
693
77051
H240
Q
R
C
L
A
G
G
H
I
S
V
L
P
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611690
615
69276
S211
I
L
W
P
R
L
N
S
F
A
S
T
W
D
W
Honey Bee
Apis mellifera
XP_395117
558
65352
K154
T
N
K
V
D
L
D
K
P
I
V
P
I
P
K
Nematode Worm
Caenorhab. elegans
NP_497751
591
67352
S187
V
F
D
Y
S
T
N
S
A
S
E
W
K
E
A
Sea Urchin
Strong. purpuratus
XP_797576
424
47124
S20
S
P
T
K
L
S
K
S
E
R
K
L
A
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
96.9
82.6
N.A.
77.2
76.8
N.A.
66.4
66.2
N.A.
55.5
N.A.
42.3
40.9
35.6
32.9
Protein Similarity:
100
99
98.4
90.3
N.A.
85.5
84.9
N.A.
77.6
80.8
N.A.
71
N.A.
57.6
57.2
54.2
45.1
P-Site Identity:
100
93.3
93.3
80
N.A.
80
80
N.A.
53.3
80
N.A.
40
N.A.
20
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
93.3
N.A.
60
N.A.
20
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
8
0
0
8
0
8
% A
% Cys:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
0
0
0
0
77
0
% D
% Glu:
62
0
0
0
0
39
0
0
8
0
8
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
70
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
54
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
70
8
8
0
8
0
0
% I
% Lys:
0
54
8
8
39
8
8
8
0
62
8
54
8
8
16
% K
% Leu:
0
8
16
70
8
16
0
0
0
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
8
0
0
8
70
8
0
% P
% Gln:
8
0
0
0
0
16
0
0
0
0
0
0
0
0
70
% Q
% Arg:
0
16
0
0
31
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
0
24
0
16
8
8
0
0
0
% S
% Thr:
8
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
39
0
0
0
0
0
0
0
0
8
8
0
8
% W
% Tyr:
0
0
0
8
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _