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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALKBH8
All Species:
26.36
Human Site:
Y374
Identified Species:
48.33
UniProt:
Q96BT7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BT7
NP_620130.2
664
75208
Y374
A
S
R
L
E
Q
E
Y
V
H
Q
V
Y
E
E
Chimpanzee
Pan troglodytes
XP_522172
664
75155
Y374
A
S
R
L
E
Q
E
Y
V
H
Q
V
Y
E
E
Rhesus Macaque
Macaca mulatta
XP_001102763
664
75113
Y374
A
S
R
L
E
Q
E
Y
V
H
Q
V
Y
E
E
Dog
Lupus familis
XP_546542
661
74257
Y374
A
S
Q
L
E
Q
D
Y
V
H
R
V
Y
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y20
664
74749
H374
A
L
E
L
E
Q
K
H
V
H
Q
V
Y
N
E
Rat
Rattus norvegicus
XP_001055538
664
74826
H374
A
L
E
L
E
Q
K
H
V
H
H
V
Y
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508849
715
79108
Y428
A
A
K
L
E
E
E
Y
V
H
R
V
Y
D
K
Chicken
Gallus gallus
XP_417166
679
76991
Y386
A
S
E
L
E
Q
Q
Y
V
H
K
V
Y
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684243
693
77051
Y398
A
C
R
L
E
S
Q
Y
V
H
Q
V
Y
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611690
615
69276
Q362
Q
A
I
T
L
E
Q
Q
N
V
H
E
V
Y
D
Honey Bee
Apis mellifera
XP_395117
558
65352
I305
K
Q
N
N
S
T
T
I
I
D
N
K
I
A
L
Nematode Worm
Caenorhab. elegans
NP_497751
591
67352
R338
K
E
F
C
D
W
D
R
K
G
E
M
S
V
P
Sea Urchin
Strong. purpuratus
XP_797576
424
47124
I171
E
W
A
S
P
S
E
I
A
N
Q
S
L
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
96.9
82.6
N.A.
77.2
76.8
N.A.
66.4
66.2
N.A.
55.5
N.A.
42.3
40.9
35.6
32.9
Protein Similarity:
100
99
98.4
90.3
N.A.
85.5
84.9
N.A.
77.6
80.8
N.A.
71
N.A.
57.6
57.2
54.2
45.1
P-Site Identity:
100
100
100
80
N.A.
66.6
60
N.A.
60
80
N.A.
80
N.A.
0
0
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
100
93.3
N.A.
86.6
N.A.
26.6
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
16
8
0
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
16
0
0
8
0
0
0
16
8
% D
% Glu:
8
8
24
0
70
16
39
0
0
0
8
8
0
47
62
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
70
16
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
16
8
0
0
0
8
0
0
% I
% Lys:
16
0
8
0
0
0
16
0
8
0
8
8
0
8
8
% K
% Leu:
0
16
0
70
8
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
8
8
8
0
0
8
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
8
8
0
0
54
24
8
0
0
47
0
0
0
0
% Q
% Arg:
0
0
31
0
0
0
0
8
0
0
16
0
0
0
0
% R
% Ser:
0
39
0
8
8
16
0
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
70
8
0
70
8
8
0
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
70
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _