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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOCK10 All Species: 23.33
Human Site: S499 Identified Species: 85.56
UniProt: Q96BY6 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BY6 NP_055504.2 2183 249312 S499 K Q A V F S V S N P H S E I V
Chimpanzee Pan troglodytes XP_516126 2186 249623 S499 K Q A V F S V S N P H S E I V
Rhesus Macaque Macaca mulatta XP_001090732 2226 253499 T586 K Q G I F S V T C P H P D I F
Dog Lupus familis XP_859786 2119 242069 T487 K V L Q G S I T H G A E P Y M
Cat Felis silvestris
Mouse Mus musculus Q8BZN6 2150 245739 S499 K Q A V F S V S D P H S E I V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509913 2265 257582 S578 K Q A I F S V S N P H T E I V
Chicken Gallus gallus XP_001234660 2188 249975 S501 K Q A L F S I S N P H S E I V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 52.2 52.7 N.A. 92.5 N.A. N.A. 82.4 82.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 69.9 71 N.A. 95.7 N.A. N.A. 89.6 90.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 53.3 13.3 N.A. 93.3 N.A. N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 40 N.A. 100 N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 72 0 0 0 0 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 15 0 0 0 15 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 15 72 0 0 % E
% Phe: 0 0 0 0 86 0 0 0 0 0 0 0 0 0 15 % F
% Gly: 0 0 15 0 15 0 0 0 0 15 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 86 0 0 0 0 % H
% Ile: 0 0 0 29 0 0 29 0 0 0 0 0 0 86 0 % I
% Lys: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 15 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 86 0 15 15 0 0 % P
% Gln: 0 86 0 15 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 100 0 72 0 0 0 58 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 29 0 0 0 15 0 0 0 % T
% Val: 0 15 0 43 0 0 72 0 0 0 0 0 0 0 72 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _