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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK10
All Species:
13.64
Human Site:
T591
Identified Species:
50
UniProt:
Q96BY6
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY6
NP_055504.2
2183
249312
T591
Q
E
S
S
K
I
S
T
E
D
L
V
K
L
V
Chimpanzee
Pan troglodytes
XP_516126
2186
249623
T591
Q
E
S
S
K
I
S
T
E
D
L
V
K
L
V
Rhesus Macaque
Macaca mulatta
XP_001090732
2226
253499
N678
Q
D
S
N
K
L
S
N
D
D
M
L
K
L
L
Dog
Lupus familis
XP_859786
2119
242069
K576
R
K
P
E
K
M
A
K
L
P
V
I
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN6
2150
245739
S591
Q
E
S
S
K
M
S
S
E
D
L
L
K
L
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509913
2265
257582
T670
Q
E
S
S
R
I
S
T
E
D
L
I
K
L
I
Chicken
Gallus gallus
XP_001234660
2188
249975
M593
Q
E
S
N
K
I
S
M
E
D
L
I
K
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
52.2
52.7
N.A.
92.5
N.A.
N.A.
82.4
82.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
69.9
71
N.A.
95.7
N.A.
N.A.
89.6
90.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
6.6
N.A.
80
N.A.
N.A.
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
100
N.A.
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
15
86
0
0
0
0
0
% D
% Glu:
0
72
0
15
0
0
0
0
72
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
58
0
0
0
0
0
43
0
0
29
% I
% Lys:
0
15
0
0
86
0
0
15
0
0
0
0
86
0
0
% K
% Leu:
0
0
0
0
0
15
0
0
15
0
72
29
15
86
15
% L
% Met:
0
0
0
0
0
29
0
15
0
0
15
0
0
0
0
% M
% Asn:
0
0
0
29
0
0
0
15
0
0
0
0
0
0
15
% N
% Pro:
0
0
15
0
0
0
0
0
0
15
0
0
0
0
0
% P
% Gln:
86
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
86
58
0
0
86
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
15
29
0
0
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _