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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM66
All Species:
17.58
Human Site:
S119
Identified Species:
38.67
UniProt:
Q96BY9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY9
NP_057211.4
339
36975
S119
V
S
C
E
G
Y
E
S
S
E
D
Q
Y
V
L
Chimpanzee
Pan troglodytes
XP_001167715
339
36948
S119
V
S
C
E
G
Y
E
S
S
E
D
Q
Y
V
L
Rhesus Macaque
Macaca mulatta
XP_001082284
303
33381
S84
S
C
E
G
Y
E
S
S
E
D
Q
Y
V
L
R
Dog
Lupus familis
XP_539993
336
36721
E115
G
K
T
M
V
S
C
E
G
Y
E
F
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q0
334
35838
S114
K
F
G
K
T
V
V
S
C
E
G
Y
E
S
S
Rat
Rattus norvegicus
Q6AYN2
334
35867
S114
K
F
G
K
T
V
V
S
C
E
G
Y
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511470
506
54221
D207
V
V
S
C
E
G
Y
D
Y
P
E
D
P
Y
V
Chicken
Gallus gallus
NP_001026317
354
38840
Y110
V
S
C
E
G
Y
N
Y
P
D
D
P
Y
I
L
Frog
Xenopus laevis
NP_001090323
300
33459
L81
H
N
R
G
W
D
G
L
D
V
Q
W
E
C
R
Zebra Danio
Brachydanio rerio
NP_001070057
345
36649
S109
V
S
C
E
G
Y
N
S
P
N
D
A
Y
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789868
385
39473
S116
V
I
C
E
G
Y
S
S
P
D
D
E
Y
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.6
83.7
N.A.
80.2
77.2
N.A.
33.4
37
45.4
38.2
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
99.1
87.6
89.6
N.A.
87.6
85.5
N.A.
43.4
50.8
59.5
52.7
N.A.
N.A.
N.A.
N.A.
52.2
P-Site Identity:
100
100
6.6
0
N.A.
13.3
13.3
N.A.
6.6
60
0
73.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
20
6.6
N.A.
20
20
N.A.
20
73.3
6.6
73.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
10
46
10
0
0
10
0
19
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
10
0
10
10
28
46
10
10
0
10
% D
% Glu:
0
0
10
46
10
10
19
10
10
37
19
10
19
10
0
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
19
19
46
10
10
0
10
0
19
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
19
0
% I
% Lys:
19
10
0
19
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
46
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
19
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
28
10
0
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
19
19
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
10
37
10
0
0
10
19
64
19
0
0
0
10
19
19
% S
% Thr:
0
0
10
0
19
0
0
0
0
0
0
0
0
0
0
% T
% Val:
55
10
0
0
10
19
19
0
0
10
0
0
10
28
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
46
10
10
10
10
0
28
46
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _