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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM66
All Species:
22.73
Human Site:
S244
Identified Species:
50
UniProt:
Q96BY9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY9
NP_057211.4
339
36975
S244
N
T
G
H
G
A
T
S
G
F
G
S
A
F
T
Chimpanzee
Pan troglodytes
XP_001167715
339
36948
S244
N
T
G
H
G
A
T
S
G
F
G
S
A
F
T
Rhesus Macaque
Macaca mulatta
XP_001082284
303
33381
G209
T
G
H
G
A
T
S
G
F
G
S
A
F
T
G
Dog
Lupus familis
XP_539993
336
36721
S240
T
G
P
H
G
A
T
S
G
F
G
S
A
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q0
334
35838
S239
N
T
G
Y
G
A
S
S
G
F
G
S
A
F
G
Rat
Rattus norvegicus
Q6AYN2
334
35867
S239
S
T
S
Y
G
A
S
S
G
F
G
S
A
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511470
506
54221
T332
N
P
G
F
G
G
T
T
G
F
D
H
P
F
S
Chicken
Gallus gallus
NP_001026317
354
38840
T235
N
S
G
P
G
F
W
T
G
L
G
A
G
G
L
Frog
Xenopus laevis
NP_001090323
300
33459
T206
G
Y
D
H
Q
S
Q
T
H
S
S
A
P
P
P
Zebra Danio
Brachydanio rerio
NP_001070057
345
36649
M234
A
W
D
N
S
Q
G
M
G
P
P
P
P
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789868
385
39473
G241
T
G
F
G
P
G
G
G
G
G
G
G
G
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.6
83.7
N.A.
80.2
77.2
N.A.
33.4
37
45.4
38.2
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
99.1
87.6
89.6
N.A.
87.6
85.5
N.A.
43.4
50.8
59.5
52.7
N.A.
N.A.
N.A.
N.A.
52.2
P-Site Identity:
100
100
0
80
N.A.
80
66.6
N.A.
46.6
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
80
N.A.
93.3
86.6
N.A.
60
53.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
46
0
0
0
0
0
28
46
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
10
0
0
10
55
0
0
10
55
10
% F
% Gly:
10
28
46
19
64
19
19
19
82
19
64
10
19
19
28
% G
% His:
0
0
10
37
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
46
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
10
10
0
0
0
0
10
10
10
28
10
19
% P
% Gln:
0
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
0
10
10
28
46
0
10
19
46
0
0
10
% S
% Thr:
28
37
0
0
0
10
37
28
0
0
0
0
0
10
28
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
19
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _