KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM66
All Species:
4.85
Human Site:
T218
Identified Species:
10.67
UniProt:
Q96BY9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY9
NP_057211.4
339
36975
T218
S
H
R
Y
Q
R
F
T
N
S
A
G
P
P
P
Chimpanzee
Pan troglodytes
XP_001167715
339
36948
T218
S
H
R
Y
Q
R
F
T
N
S
A
G
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001082284
303
33381
N183
H
R
Y
Q
R
F
T
N
S
A
G
P
P
P
P
Dog
Lupus familis
XP_539993
336
36721
Y214
Y
P
P
N
S
Y
H
Y
Q
R
F
T
N
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q0
334
35838
A213
S
E
H
S
Q
R
F
A
S
A
A
G
A
P
P
Rat
Rattus norvegicus
Q6AYN2
334
35867
A213
S
Q
H
S
Q
R
F
A
G
T
A
G
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511470
506
54221
F306
H
W
Q
D
Q
Q
G
F
S
H
P
G
P
P
P
Chicken
Gallus gallus
NP_001026317
354
38840
G209
H
Q
A
P
P
P
P
G
F
K
S
S
F
T
D
Frog
Xenopus laevis
NP_001090323
300
33459
Y180
V
I
L
A
Y
G
V
Y
K
L
F
L
S
G
P
Zebra Danio
Brachydanio rerio
NP_001070057
345
36649
P208
Y
K
M
F
L
C
S
P
T
H
G
H
Q
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789868
385
39473
I215
A
S
L
T
T
H
K
I
K
K
N
K
W
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.6
83.7
N.A.
80.2
77.2
N.A.
33.4
37
45.4
38.2
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
99.1
87.6
89.6
N.A.
87.6
85.5
N.A.
43.4
50.8
59.5
52.7
N.A.
N.A.
N.A.
N.A.
52.2
P-Site Identity:
100
100
20
0
N.A.
53.3
53.3
N.A.
33.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
40
0
N.A.
66.6
60
N.A.
53.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
19
0
19
37
0
19
0
19
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
10
37
10
10
0
19
0
10
0
10
% F
% Gly:
0
0
0
0
0
10
10
10
10
0
19
46
0
19
0
% G
% His:
28
19
19
0
0
10
10
0
0
19
0
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
0
19
19
0
10
0
0
0
% K
% Leu:
0
0
19
0
10
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
19
0
10
0
10
0
0
% N
% Pro:
0
10
10
10
10
10
10
10
0
0
10
10
37
55
64
% P
% Gln:
0
19
10
10
46
10
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
10
19
0
10
37
0
0
0
10
0
0
0
0
0
% R
% Ser:
37
10
0
19
10
0
10
0
28
19
10
10
10
10
0
% S
% Thr:
0
0
0
10
10
0
10
19
10
10
0
10
0
19
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
19
0
10
19
10
10
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _