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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM66
All Species:
10
Human Site:
Y138
Identified Species:
22
UniProt:
Q96BY9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY9
NP_057211.4
339
36975
Y138
G
L
E
Y
N
L
D
Y
T
E
L
G
L
Q
K
Chimpanzee
Pan troglodytes
XP_001167715
339
36948
Y138
G
L
E
Y
N
L
D
Y
T
E
L
G
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082284
303
33381
T103
L
E
Y
N
L
D
Y
T
E
L
G
L
Q
K
L
Dog
Lupus familis
XP_539993
336
36721
Y134
R
G
S
C
G
L
E
Y
N
L
D
Y
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q0
334
35838
L133
V
L
R
G
S
C
G
L
E
Y
N
L
D
Y
T
Rat
Rattus norvegicus
Q6AYN2
334
35867
L133
I
L
R
G
S
C
G
L
E
Y
N
L
D
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511470
506
54221
E226
C
S
L
E
Y
N
L
E
L
T
E
H
G
Q
R
Chicken
Gallus gallus
NP_001026317
354
38840
L129
S
L
L
F
R
L
E
L
T
K
E
G
E
W
K
Frog
Xenopus laevis
NP_001090323
300
33459
V100
N
S
Y
R
F
G
K
V
E
V
S
C
E
G
F
Zebra Danio
Brachydanio rerio
NP_001070057
345
36649
L128
G
L
E
Y
T
L
E
L
T
A
E
G
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789868
385
39473
Y135
G
L
E
F
T
L
E
Y
T
K
E
G
M
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.6
83.7
N.A.
80.2
77.2
N.A.
33.4
37
45.4
38.2
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
99.1
87.6
89.6
N.A.
87.6
85.5
N.A.
43.4
50.8
59.5
52.7
N.A.
N.A.
N.A.
N.A.
52.2
P-Site Identity:
100
100
0
13.3
N.A.
6.6
6.6
N.A.
6.6
33.3
0
53.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
6.6
26.6
N.A.
13.3
13.3
N.A.
13.3
53.3
0
66.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
10
0
0
10
0
19
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
10
19
0
0
0
10
0
19
0
0
% D
% Glu:
0
10
37
10
0
0
37
10
37
19
37
0
19
10
0
% E
% Phe:
0
0
0
19
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
37
10
0
19
10
10
19
0
0
0
10
46
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
19
0
0
10
10
28
% K
% Leu:
10
64
19
0
10
55
10
37
10
19
19
28
19
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
10
19
10
0
0
10
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
46
19
% Q
% Arg:
10
0
19
10
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
19
10
0
19
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
19
0
0
10
46
10
0
0
10
0
19
% T
% Val:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
19
28
10
0
10
37
0
19
0
10
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _