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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM66
All Species:
12.12
Human Site:
Y162
Identified Species:
26.67
UniProt:
Q96BY9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BY9
NP_057211.4
339
36975
Y162
F
A
S
F
S
D
Y
Y
Y
K
W
S
S
A
D
Chimpanzee
Pan troglodytes
XP_001167715
339
36948
Y162
F
A
S
F
S
D
Y
Y
Y
K
W
S
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001082284
303
33381
Y127
A
S
F
S
D
Y
Y
Y
K
W
Y
S
A
D
S
Dog
Lupus familis
XP_539993
336
36721
F158
K
N
H
G
F
N
S
F
S
N
Y
Y
D
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Q0
334
35838
S157
S
G
K
H
Q
G
F
S
D
Y
Y
H
K
L
Y
Rat
Rattus norvegicus
Q6AYN2
334
35867
S157
S
G
K
H
Q
S
F
S
D
Y
Y
H
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511470
506
54221
S250
F
S
Y
F
S
S
R
S
Q
K
A
D
M
A
E
Chicken
Gallus gallus
NP_001026317
354
38840
D153
G
Y
Y
A
S
T
K
D
S
S
D
S
G
A
G
Frog
Xenopus laevis
NP_001090323
300
33459
Y124
R
G
S
C
G
L
E
Y
T
L
E
L
T
E
E
Zebra Danio
Brachydanio rerio
NP_001070057
345
36649
F152
A
S
N
F
F
Q
G
F
S
N
Q
K
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789868
385
39473
S159
Y
Y
G
K
D
D
G
S
Y
D
N
T
Y
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.6
83.7
N.A.
80.2
77.2
N.A.
33.4
37
45.4
38.2
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
99.1
87.6
89.6
N.A.
87.6
85.5
N.A.
43.4
50.8
59.5
52.7
N.A.
N.A.
N.A.
N.A.
52.2
P-Site Identity:
100
100
20
0
N.A.
0
0
N.A.
33.3
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
40
20
N.A.
13.3
13.3
N.A.
46.6
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
0
10
0
0
0
0
0
0
10
0
10
37
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
28
0
10
19
10
10
10
10
10
19
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
19
% E
% Phe:
28
0
10
37
19
0
19
19
0
0
0
0
0
0
0
% F
% Gly:
10
28
10
10
10
10
19
0
0
0
0
0
10
0
10
% G
% His:
0
0
10
19
0
0
0
0
0
0
0
19
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
19
10
0
0
10
0
10
28
0
10
19
10
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
10
0
10
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
10
0
0
0
19
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
10
0
0
10
0
10
0
10
10
10
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
19
28
28
10
37
19
10
37
28
10
0
37
19
0
19
% S
% Thr:
0
0
0
0
0
10
0
0
10
0
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
0
% W
% Tyr:
10
19
19
0
0
10
28
37
28
19
37
10
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _