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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD4 All Species: 13.94
Human Site: S112 Identified Species: 27.88
UniProt: Q96BZ4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BZ4 NP_620145.2 506 55626 S112 D L P S A A G S P S A Q P L G
Chimpanzee Pan troglodytes XP_524268 446 49752 S88 C E A V L V E S I P E G L D F
Rhesus Macaque Macaca mulatta XP_001094274 490 54730 S106 S T G N P S T S Q A W L G L L
Dog Lupus familis XP_855517 602 65000 S207 D L P S A A G S P S A Q P L A
Cat Felis silvestris
Mouse Mus musculus Q8BG07 503 56135 S110 D L P F A A G S P T A Q P L A
Rat Rattus norvegicus Q5FVH2 488 54381 S106 T T S N P S T S Q A W L G L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516055 313 34760
Chicken Gallus gallus XP_421399 517 59127 S106 D L A F E I N S T A A K P L Y
Frog Xenopus laevis Q6PB03 493 56202 F107 S T I N P S I F Q S W M N I I
Zebra Danio Brachydanio rerio XP_001921976 479 53770 A107 D L R R N S S A G S D L Y E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17405 516 58554 F139 S I P I G L P F K T N N H T A
Sea Urchin Strong. purpuratus XP_793309 435 48586 P76 V I L A E S M P L N L T F P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.1 42.4 66.2 N.A. 74.5 42.6 N.A. 41.7 49.9 41.5 41.1 N.A. N.A. N.A. 31.5 37.7
Protein Similarity: 100 53.7 58.8 71.9 N.A. 82.2 58 N.A. 49.5 67.8 59.8 59.6 N.A. N.A. N.A. 52.3 53.7
P-Site Identity: 100 6.6 13.3 93.3 N.A. 80 13.3 N.A. 0 40 6.6 20 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 6.6 33.3 93.3 N.A. 86.6 33.3 N.A. 0 53.3 26.6 33.3 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 25 25 0 9 0 25 34 0 0 0 34 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 0 0 0 0 0 0 0 0 9 0 0 9 9 % D
% Glu: 0 9 0 0 17 0 9 0 0 0 9 0 0 9 0 % E
% Phe: 0 0 0 17 0 0 0 17 0 0 0 0 9 0 9 % F
% Gly: 0 0 9 0 9 0 25 0 9 0 0 9 17 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 17 9 9 0 9 9 0 9 0 0 0 0 9 9 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % K
% Leu: 0 42 9 0 9 9 0 0 9 0 9 25 9 50 17 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 25 9 0 9 0 0 9 9 9 9 0 0 % N
% Pro: 0 0 34 0 25 0 9 9 25 9 0 0 34 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 25 0 0 25 0 0 0 % Q
% Arg: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 25 0 9 17 0 42 9 59 0 34 0 0 0 0 0 % S
% Thr: 9 25 0 0 0 0 17 0 9 17 0 9 0 9 0 % T
% Val: 9 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _