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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX58
All Species:
16.78
Human Site:
S673
Identified Species:
36.92
UniProt:
Q96C10
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C10
NP_077024.2
678
76613
S673
Q
H
C
A
E
N
L
S
D
L
S
L
D
_
_
Chimpanzee
Pan troglodytes
XP_001167051
678
76609
S673
Q
H
C
A
Q
N
L
S
D
L
S
L
D
_
_
Rhesus Macaque
Macaca mulatta
XP_001108799
678
76729
S673
Q
H
C
A
Q
N
L
S
D
L
S
L
D
_
_
Dog
Lupus familis
XP_850033
678
76952
A673
Q
H
C
A
Q
N
L
A
D
L
S
L
D
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q99J87
678
76708
S673
Q
D
C
T
Q
S
L
S
E
L
S
L
D
_
_
Rat
Rattus norvegicus
NP_001092258
678
76894
S673
R
D
C
T
Q
S
L
S
D
L
S
L
D
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
N897
C
S
K
W
K
T
F
N
F
V
R
I
P
F
D
Chicken
Gallus gallus
XP_422031
1285
144686
Frog
Xenopus laevis
NP_001085915
682
79226
E675
Q
H
V
R
I
H
P
E
L
L
V
H
F
E
D
Zebra Danio
Brachydanio rerio
XP_694124
738
84421
E728
Q
H
A
D
L
L
V
E
D
S
E
D
E
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176480
823
93488
P715
D
D
L
G
K
Q
D
P
E
G
V
Q
E
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
84.6
N.A.
78.9
79.1
N.A.
26.9
23.7
51.1
38.8
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.4
97.9
91.4
N.A.
87.6
87.7
N.A.
43.9
35.8
67.4
57.1
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
92.3
92.3
84.6
N.A.
61.5
61.5
N.A.
0
0
20
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
84.6
84.6
N.A.
26.6
0
26.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
37
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
10
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
28
0
10
0
0
10
0
55
0
0
10
55
10
19
% D
% Glu:
0
0
0
0
10
0
0
19
19
0
10
0
19
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
55
0
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
19
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
10
10
55
0
10
64
0
55
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
37
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% P
% Gln:
64
0
0
0
46
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
0
19
0
46
0
10
55
0
0
0
0
% S
% Thr:
0
0
0
19
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
0
10
19
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
55
% _