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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD2
All Species:
17.88
Human Site:
Y83
Identified Species:
32.78
UniProt:
Q96C19
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C19
NP_077305.2
240
26697
Y83
S
R
R
V
F
N
P
Y
T
E
F
K
E
F
S
Chimpanzee
Pan troglodytes
XP_001156210
410
44344
Y253
S
R
R
V
F
N
P
Y
T
E
F
K
E
F
S
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
D25
A
Q
Q
E
E
R
L
D
E
I
N
K
Q
F
L
Dog
Lupus familis
XP_848956
248
27200
G88
A
F
G
V
C
S
P
G
L
E
S
Q
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y0
240
26773
Y83
S
R
R
V
F
N
P
Y
T
E
F
K
E
F
S
Rat
Rattus norvegicus
Q4FZY0
239
26741
Y82
S
R
R
V
F
N
P
Y
T
E
F
K
E
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
L47
G
F
I
D
L
M
E
L
K
L
M
M
E
K
L
Chicken
Gallus gallus
P09860
161
18412
K39
E
D
G
C
I
S
T
K
E
L
G
K
V
M
R
Frog
Xenopus laevis
NP_001089944
202
23367
D70
R
Q
F
D
A
G
H
D
G
F
I
D
L
M
E
Zebra Danio
Brachydanio rerio
NP_001038676
233
26492
Y76
S
M
K
V
F
N
P
Y
T
E
F
K
E
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
Q70
F
P
E
F
S
R
N
Q
I
K
D
Y
Q
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
K69
F
I
D
M
M
E
L
K
Y
M
M
E
K
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
L44
L
G
S
L
L
R
A
L
G
V
K
P
S
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
25.8
62
N.A.
94.1
93.3
N.A.
60
20
70.4
75
N.A.
45.8
N.A.
N.A.
53.3
Protein Similarity:
100
58.2
37.9
68.9
N.A.
97
96.6
N.A.
64.1
38.7
76.6
83.7
N.A.
60.8
N.A.
N.A.
63.7
P-Site Identity:
100
100
13.3
20
N.A.
100
100
N.A.
6.6
6.6
0
86.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
40
46.6
N.A.
100
100
N.A.
6.6
13.3
6.6
93.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
16
0
0
0
16
0
0
8
8
0
0
8
% D
% Glu:
8
0
8
8
8
8
8
0
16
47
0
8
47
0
16
% E
% Phe:
16
16
8
8
39
0
0
0
0
8
39
0
0
47
0
% F
% Gly:
8
8
16
0
0
8
0
8
16
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
0
8
8
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
16
8
8
8
54
8
16
0
% K
% Leu:
8
0
0
8
16
0
16
16
8
16
0
0
16
8
16
% L
% Met:
0
8
0
8
8
8
0
0
0
8
16
8
0
16
0
% M
% Asn:
0
0
0
0
0
39
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
47
0
0
0
0
8
0
8
0
% P
% Gln:
0
16
8
0
0
0
0
8
0
0
0
8
16
8
0
% Q
% Arg:
8
31
31
0
0
24
0
0
0
0
0
0
0
0
8
% R
% Ser:
39
0
8
0
8
16
0
0
0
0
8
0
8
0
39
% S
% Thr:
0
0
0
0
0
0
8
0
39
0
0
0
0
0
8
% T
% Val:
0
0
0
47
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _