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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYTL4 All Species: 8.18
Human Site: S488 Identified Species: 18
UniProt: Q96C24 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96C24 NP_001123368.1 671 76010 S488 H G K I S A E S P T G L P S H
Chimpanzee Pan troglodytes XP_528937 730 81383 V549 Q Y K G E L T V V L R Y I P P
Rhesus Macaque Macaca mulatta XP_001092576 609 67758 P432 T Q S F C W H P L R A K A E K
Dog Lupus familis XP_537994 732 81717 V551 H Y K G E L T V S L R Y I P P
Cat Felis silvestris
Mouse Mus musculus Q9R0Q1 673 76003 S490 H G K I S T E S S P G L P A H
Rat Rattus norvegicus Q8VHQ7 672 75882 S489 H G K I S T E S S P G L P A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513251 493 55509 E316 M D M V S E E E E E E D I D N
Chicken Gallus gallus P47191 424 47487 K247 H D I I G E Y K V A M N T V D
Frog Xenopus laevis NP_001086460 547 61814 Y370 L G S M M S I Y S E A G D F G
Zebra Danio Brachydanio rerio NP_001074457 689 76692 L504 G K A V P Q S L L S P F D Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 V297 D Q I G E V K V P L C T I D L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.3 32.6 42.9 N.A. 90.1 91.3 N.A. 49.6 22.3 44.2 49.3 N.A. 23.3 N.A. N.A. N.A.
Protein Similarity: 100 58.9 50.9 60.2 N.A. 95 95.6 N.A. 59 37.7 60.3 66.9 N.A. 39.7 N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 13.3 N.A. 73.3 73.3 N.A. 13.3 13.3 6.6 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 0 13.3 N.A. 80 80 N.A. 26.6 13.3 20 20 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 10 19 0 10 19 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 19 0 0 0 0 0 0 0 0 0 10 19 19 10 % D
% Glu: 0 0 0 0 28 19 37 10 10 19 10 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 10 0 10 0 % F
% Gly: 10 37 0 28 10 0 0 0 0 0 28 10 0 0 10 % G
% His: 46 0 0 0 0 0 10 0 0 0 0 0 0 0 28 % H
% Ile: 0 0 19 37 0 0 10 0 0 0 0 0 37 0 0 % I
% Lys: 0 10 46 0 0 0 10 10 0 0 0 10 0 0 10 % K
% Leu: 10 0 0 0 0 19 0 10 19 28 0 28 0 0 10 % L
% Met: 10 0 10 10 10 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 0 0 0 10 0 0 10 19 19 10 0 28 19 19 % P
% Gln: 10 19 0 0 0 10 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 19 0 0 0 0 % R
% Ser: 0 0 19 0 37 10 10 28 37 10 0 0 0 10 0 % S
% Thr: 10 0 0 0 0 19 19 0 0 10 0 10 10 0 0 % T
% Val: 0 0 0 19 0 10 0 28 19 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 10 10 0 0 0 19 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _