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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf43
All Species:
4.55
Human Site:
S205
Identified Species:
12.5
UniProt:
Q96C57
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C57
NP_075046.1
262
28171
S205
K
K
V
A
S
V
D
S
A
V
A
A
T
T
P
Chimpanzee
Pan troglodytes
XP_509434
263
28239
S206
K
K
V
A
S
V
D
S
A
V
A
A
T
T
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854331
269
28946
V209
K
E
A
S
A
D
L
V
A
A
T
T
I
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UY34
256
27613
D199
K
K
A
K
K
K
V
D
N
A
D
L
A
A
A
Rat
Rattus norvegicus
Q5I034
277
30038
A220
K
K
K
A
K
K
K
A
D
A
D
L
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506204
277
30025
L204
V
I
H
S
C
V
I
L
G
S
P
E
V
W
P
Chicken
Gallus gallus
XP_415259
287
31784
K226
K
K
K
K
K
K
I
K
G
E
N
K
T
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082895
237
26920
K181
M
K
K
K
K
K
R
K
T
S
S
E
E
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197247
224
25354
P168
D
S
A
S
H
V
I
P
K
R
T
R
T
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
72.1
N.A.
68.3
65.3
N.A.
41.1
36.2
N.A.
36.2
N.A.
N.A.
N.A.
N.A.
20.9
Protein Similarity:
100
99.6
N.A.
79.1
N.A.
77.8
74.7
N.A.
53.7
50.1
N.A.
49.6
N.A.
N.A.
N.A.
N.A.
31.3
P-Site Identity:
100
100
N.A.
20
N.A.
13.3
20
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
40
N.A.
13.3
26.6
N.A.
20
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
34
12
0
0
12
34
34
23
23
23
23
23
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
12
23
12
12
0
23
0
0
0
12
% D
% Glu:
0
12
0
0
0
0
0
0
0
12
0
23
12
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% G
% His:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
34
0
0
0
0
0
12
0
0
% I
% Lys:
67
67
34
34
45
45
12
23
12
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
12
0
0
0
23
0
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
34
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
12
0
0
12
0
12
0
0
0
% R
% Ser:
0
12
0
34
23
0
0
23
0
23
12
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
23
12
45
34
0
% T
% Val:
12
0
23
0
0
45
12
12
0
23
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _