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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROPN1L
All Species:
7.88
Human Site:
S225
Identified Species:
15.76
UniProt:
Q96C74
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C74
NP_114122.2
230
26107
S225
L
L
E
S
I
E
N
S
E
D
V
G
H
_
_
Chimpanzee
Pan troglodytes
XP_517631
230
26090
S225
L
L
E
N
I
E
N
S
E
D
V
G
H
_
_
Rhesus Macaque
Macaca mulatta
XP_001085948
198
22364
Dog
Lupus familis
XP_535790
218
24681
F211
G
M
I
G
L
S
D
F
F
V
L
T
R
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ00
230
25923
A225
I
E
S
L
E
E
K
A
L
E
A
E
H
_
_
Rat
Rattus norvegicus
Q4KLL5
212
23942
T204
L
I
K
V
N
D
F
T
Q
N
P
R
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519179
218
24250
F211
G
L
I
G
V
S
D
F
L
I
S
A
K
K
V
Chicken
Gallus gallus
XP_419011
218
24423
Q213
L
L
R
N
F
Q
S
Q
P
S
T
Q
L
_
_
Frog
Xenopus laevis
Q4V7T8
219
24389
Q214
P
R
N
F
L
S
S
Q
C
P
L
L
S
_
_
Zebra Danio
Brachydanio rerio
Q66IC9
218
24152
T211
M
V
Q
P
S
N
F
T
S
L
H
T
A
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121035
280
31690
P261
V
Q
E
G
M
V
G
P
R
N
L
R
H
M
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793854
224
25048
R211
Q
N
G
A
V
Q
P
R
N
F
L
H
P
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
82.6
79.5
N.A.
76
38.2
N.A.
68.2
56.5
57.3
53.4
N.A.
N.A.
20.7
N.A.
50.4
Protein Similarity:
100
99.5
84.7
89.1
N.A.
87.8
58.7
N.A.
82.6
76
75.2
67.3
N.A.
N.A.
37.5
N.A.
70
P-Site Identity:
100
92.3
0
0
N.A.
15.3
6.6
N.A.
6.6
15.3
0
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
0
26.6
N.A.
38.4
46.6
N.A.
20
38.4
23
26.6
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
9
17
0
0
17
0
0
0
9
0
% D
% Glu:
0
9
25
0
9
25
0
0
17
9
0
9
0
9
0
% E
% Phe:
0
0
0
9
9
0
17
17
9
9
0
0
0
0
0
% F
% Gly:
17
0
9
25
0
0
9
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
34
0
0
% H
% Ile:
9
9
17
0
17
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
0
0
0
9
17
9
% K
% Leu:
34
34
0
9
17
0
0
0
17
9
34
9
9
0
9
% L
% Met:
9
9
0
0
9
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
9
17
9
9
17
0
9
17
0
0
0
0
9
% N
% Pro:
9
0
0
9
0
0
9
9
9
9
9
0
9
0
0
% P
% Gln:
9
9
9
0
0
17
0
17
9
0
0
9
0
0
0
% Q
% Arg:
0
9
9
0
0
0
0
9
9
0
0
17
9
9
0
% R
% Ser:
0
0
9
9
9
25
17
17
9
9
9
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
9
17
0
0
0
% T
% Val:
9
9
0
9
17
9
0
0
0
9
17
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
42
% _