Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS12 All Species: 27.88
Human Site: S429 Identified Species: 51.11
UniProt: Q96CB8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB8 NP_001135943.1 462 48808 S429 S E S S S S P S A S L K G P T
Chimpanzee Pan troglodytes XP_517380 462 48786 S429 S E S S S S P S A S L K G P T
Rhesus Macaque Macaca mulatta XP_001084188 462 48791 S429 S E S S S S P S A S L K G P T
Dog Lupus familis XP_545012 788 84125 S755 S E L S S S L S A C P K G P T
Cat Felis silvestris
Mouse Mus musculus Q9D168 461 48550 S428 S E T S S S T S A S L K G P T
Rat Rattus norvegicus Q68FR3 461 48459 S428 S E T S S S T S A S L K G P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511131 200 19036 A182 S Q E S Q L N A M K R L Q M V
Chicken Gallus gallus XP_420500 509 53231 N474 K T T A D A G N Q S A S L K G
Frog Xenopus laevis Q6DJM6 464 48894 D426 S S N K V A V D P S M Q Q S G
Zebra Danio Brachydanio rerio Q6IQU7 479 49572 S431 N G G N S A G S S S S S G N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651507 328 34315 S310 S T K S S S K S S S S K H H E
Honey Bee Apis mellifera XP_393298 287 32118 S269 T Q S S K K N S S S N S P A L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195035 333 36996 K315 E E T S Y D E K E S F K A M N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.9 54.9 N.A. 91.3 90.6 N.A. 29 73.2 67.4 60.1 N.A. 22.5 23.5 N.A. 25.1
Protein Similarity: 100 99.7 99.7 56.3 N.A. 95.8 95.4 N.A. 32.6 79.1 76.7 72.4 N.A. 39.3 37.4 N.A. 38.7
P-Site Identity: 100 100 100 73.3 N.A. 86.6 86.6 N.A. 13.3 6.6 13.3 26.6 N.A. 46.6 26.6 N.A. 26.6
P-Site Similarity: 100 100 100 73.3 N.A. 93.3 93.3 N.A. 26.6 33.3 40 53.3 N.A. 53.3 46.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 24 0 8 47 0 8 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % D
% Glu: 8 54 8 0 0 0 8 0 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 16 0 0 0 0 0 54 0 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 8 8 8 8 8 0 8 0 62 0 8 0 % K
% Leu: 0 0 8 0 0 8 8 0 0 0 39 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 16 0 % M
% Asn: 8 0 8 8 0 0 16 8 0 0 8 0 0 8 16 % N
% Pro: 0 0 0 0 0 0 24 0 8 0 8 0 8 47 0 % P
% Gln: 0 16 0 0 8 0 0 0 8 0 0 8 16 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 70 8 31 77 62 54 0 70 24 85 16 24 0 8 0 % S
% Thr: 8 16 31 0 0 0 16 0 0 0 0 0 0 0 47 % T
% Val: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _