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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM4SF18
All Species:
11.21
Human Site:
T140
Identified Species:
30.83
UniProt:
Q96CE8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CE8
NP_620141.1
201
22277
T140
G
T
A
G
R
F
L
T
D
S
S
I
W
I
Q
Chimpanzee
Pan troglodytes
XP_001140185
239
25958
L140
A
S
T
E
G
Q
Y
L
L
D
T
S
T
W
S
Rhesus Macaque
Macaca mulatta
XP_001108938
201
22181
T140
G
T
A
G
R
F
L
T
D
S
S
I
W
I
Q
Dog
Lupus familis
XP_534302
201
22071
T140
G
T
S
G
R
F
L
T
D
S
S
R
W
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64302
202
22225
L140
A
S
T
E
G
Q
Y
L
L
N
S
S
M
W
S
Rat
Rattus norvegicus
Q9EQL5
202
21466
Q140
D
G
D
Y
L
N
D
Q
A
L
W
S
K
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234069
201
22200
R140
D
T
V
G
G
Y
L
R
D
Y
S
A
W
S
Q
Frog
Xenopus laevis
NP_001086773
213
23629
G140
P
F
Q
N
T
G
G
G
Y
L
V
V
Y
T
S
Zebra Danio
Brachydanio rerio
NP_001003489
198
20755
S140
F
T
D
G
N
Y
L
S
N
R
T
M
W
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41
97
91
N.A.
39.1
36.6
N.A.
N.A.
58.7
51.6
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.4
98
96
N.A.
61.3
58.9
N.A.
N.A.
76.1
67.6
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
73.3
N.A.
6.6
0
N.A.
N.A.
46.6
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
86.6
N.A.
20
6.6
N.A.
N.A.
53.3
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
23
0
0
0
0
0
12
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
23
0
23
0
0
0
12
0
45
12
0
0
0
0
0
% D
% Glu:
0
0
0
23
0
0
0
0
0
0
0
0
0
12
23
% E
% Phe:
12
12
0
0
0
34
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
12
0
56
34
12
12
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
23
0
23
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
0
12
0
56
23
23
23
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% M
% Asn:
0
0
0
12
12
12
0
0
12
12
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
23
0
12
0
0
0
0
0
0
34
% Q
% Arg:
0
0
0
0
34
0
0
12
0
12
0
12
0
0
0
% R
% Ser:
0
23
12
0
0
0
0
12
0
34
56
34
0
12
34
% S
% Thr:
0
56
23
0
12
0
0
34
0
0
23
0
12
23
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
56
23
0
% W
% Tyr:
0
0
0
12
0
23
23
0
12
12
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _