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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4C
All Species:
44.55
Human Site:
S150
Identified Species:
75.38
UniProt:
Q96CF2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CF2
NP_689497.1
233
26411
S150
Q
E
I
S
E
A
F
S
Q
R
V
G
F
G
D
Chimpanzee
Pan troglodytes
XP_528179
346
37934
S263
Q
E
I
S
E
A
F
S
Q
R
V
G
F
G
D
Rhesus Macaque
Macaca mulatta
XP_001093735
233
26393
S150
Q
E
I
S
E
A
F
S
Q
R
V
G
F
G
D
Dog
Lupus familis
XP_535115
236
26393
S150
Q
E
I
S
E
A
F
S
Q
R
V
G
F
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7F7
232
26261
S150
Q
E
I
S
E
A
F
S
Q
R
V
Q
F
A
D
Rat
Rattus norvegicus
Q569C1
232
26305
S150
Q
E
I
S
E
A
F
S
Q
R
V
Q
F
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507822
358
38284
S277
Q
E
M
S
D
A
F
S
Q
R
V
G
F
G
D
Chicken
Gallus gallus
Q5ZHP5
227
25137
S152
D
E
I
S
T
A
I
S
K
P
V
G
F
G
E
Frog
Xenopus laevis
Q6GNN8
227
25461
S154
Q
E
I
S
D
A
I
S
R
P
V
G
F
G
D
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
S148
Q
E
I
S
D
A
I
S
R
P
V
G
F
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610462
226
25425
S146
R
E
I
S
D
A
I
S
N
P
V
A
F
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZE4
219
24314
A144
K
Q
I
Q
E
A
L
A
T
P
M
G
A
A
A
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
S148
D
E
I
S
D
A
I
S
R
P
L
I
T
G
A
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
T149
N
E
I
A
T
A
I
T
S
A
N
I
G
Q
P
Conservation
Percent
Protein Identity:
100
67
98.7
88.1
N.A.
86.6
87.1
N.A.
41.3
64.3
71.2
63.5
N.A.
49.3
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
99.5
91
N.A.
92.6
93.1
N.A.
50.8
79.4
83.2
79.8
N.A.
69
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
60
73.3
66.6
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
73.3
86.6
86.6
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
34.1
32.1
Protein Similarity:
N.A.
N.A.
N.A.
53.2
57
57
P-Site Identity:
N.A.
N.A.
N.A.
26.6
40
20
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
100
0
8
0
8
0
8
8
22
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
36
0
0
0
0
0
0
0
0
0
58
% D
% Glu:
0
93
0
0
50
0
0
0
0
0
0
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
50
0
0
0
0
0
79
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
65
8
72
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
93
0
0
0
43
0
0
0
0
15
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
8
% P
% Gln:
65
8
0
8
0
0
0
0
50
0
0
15
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
22
50
0
0
0
0
0
% R
% Ser:
0
0
0
86
0
0
0
86
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
8
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
79
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _