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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4C
All Species:
25.45
Human Site:
S190
Identified Species:
43.08
UniProt:
Q96CF2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CF2
NP_689497.1
233
26411
S190
I
R
L
P
N
V
P
S
S
S
L
P
A
Q
P
Chimpanzee
Pan troglodytes
XP_528179
346
37934
S303
I
R
L
P
N
V
P
S
S
S
L
P
A
Q
P
Rhesus Macaque
Macaca mulatta
XP_001093735
233
26393
S190
I
R
L
P
N
V
P
S
S
S
L
P
A
Q
P
Dog
Lupus familis
XP_535115
236
26393
S190
I
R
L
P
N
V
P
S
S
S
L
P
A
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7F7
232
26261
S190
L
E
L
P
N
V
P
S
S
S
L
P
A
Q
P
Rat
Rattus norvegicus
Q569C1
232
26305
S190
M
E
L
P
N
V
P
S
S
S
L
P
A
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507822
358
38284
S316
I
R
L
P
S
V
P
S
P
S
L
F
P
A
P
Chicken
Gallus gallus
Q5ZHP5
227
25137
N181
E
Q
E
E
L
D
K
N
L
L
E
I
S
G
P
Frog
Xenopus laevis
Q6GNN8
227
25461
N186
D
L
N
S
Q
M
A
N
V
N
L
P
S
V
P
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
Q180
E
L
D
K
D
L
L
Q
I
S
G
P
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610462
226
25425
E181
K
E
I
I
G
I
P
E
P
T
P
T
L
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZE4
219
24314
Q176
E
L
E
S
Q
L
L
Q
P
A
T
T
A
P
P
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
N188
K
I
V
N
N
N
V
N
A
A
P
I
S
E
N
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
G183
S
K
L
H
E
T
G
G
S
I
P
V
H
D
K
Conservation
Percent
Protein Identity:
100
67
98.7
88.1
N.A.
86.6
87.1
N.A.
41.3
64.3
71.2
63.5
N.A.
49.3
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
99.5
91
N.A.
92.6
93.1
N.A.
50.8
79.4
83.2
79.8
N.A.
69
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
66.6
6.6
20
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
26.6
46.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
34.1
32.1
Protein Similarity:
N.A.
N.A.
N.A.
53.2
57
57
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
15
0
0
50
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
0
0
0
0
0
15
0
% D
% Glu:
22
22
15
8
8
0
0
8
0
0
8
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
8
0
0
8
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
36
8
8
8
0
8
0
0
8
8
0
15
0
0
0
% I
% Lys:
15
8
0
8
0
0
8
0
0
0
0
0
0
0
8
% K
% Leu:
8
22
58
0
8
15
15
0
8
8
58
0
8
0
0
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
50
8
0
22
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
50
0
0
58
0
22
0
22
58
8
15
72
% P
% Gln:
0
8
0
0
15
0
0
15
0
0
0
0
0
43
0
% Q
% Arg:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
15
8
0
0
50
50
58
0
0
22
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
8
15
0
0
0
% T
% Val:
0
0
8
0
0
50
8
0
8
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _