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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4C
All Species:
17.58
Human Site:
S210
Identified Species:
29.74
UniProt:
Q96CF2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CF2
NP_689497.1
233
26411
S210
M
S
S
T
A
R
R
S
R
A
A
S
S
Q
R
Chimpanzee
Pan troglodytes
XP_528179
346
37934
S323
M
S
S
T
A
R
R
S
R
A
A
S
S
R
R
Rhesus Macaque
Macaca mulatta
XP_001093735
233
26393
S210
M
S
S
T
A
R
R
S
R
A
A
S
S
R
R
Dog
Lupus familis
XP_535115
236
26393
T210
G
T
S
G
V
S
S
T
A
H
R
S
R
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7F7
232
26261
S210
M
P
S
S
V
H
R
S
R
A
A
S
S
R
R
Rat
Rattus norvegicus
Q569C1
232
26305
S210
V
P
S
S
V
H
R
S
R
A
A
S
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507822
358
38284
F336
R
P
S
T
S
H
Q
F
R
G
A
S
S
K
R
Chicken
Gallus gallus
Q5ZHP5
227
25137
I201
P
N
V
P
S
I
S
I
P
S
K
P
A
K
K
Frog
Xenopus laevis
Q6GNN8
227
25461
P206
S
T
K
L
P
S
R
P
A
S
S
R
K
K
V
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
K200
P
S
N
P
L
P
K
K
T
A
V
A
Q
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610462
226
25425
K201
L
P
E
K
A
K
E
K
K
K
A
T
T
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZE4
219
24314
A196
V
P
A
G
R
Q
P
A
R
P
V
P
Q
K
R
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
K208
S
V
P
S
N
K
I
K
Q
S
E
N
S
V
K
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
G203
A
G
T
G
A
L
K
G
K
E
K
A
K
A
V
Conservation
Percent
Protein Identity:
100
67
98.7
88.1
N.A.
86.6
87.1
N.A.
41.3
64.3
71.2
63.5
N.A.
49.3
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
99.5
91
N.A.
92.6
93.1
N.A.
50.8
79.4
83.2
79.8
N.A.
69
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
13.3
N.A.
66.6
60
N.A.
46.6
0
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
80
80
N.A.
66.6
40
33.3
46.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
34.1
32.1
Protein Similarity:
N.A.
N.A.
N.A.
53.2
57
57
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
36
0
0
8
15
43
50
15
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
22
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
22
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
15
15
22
15
8
15
0
15
36
22
% K
% Leu:
8
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% L
% Met:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
15
36
8
15
8
8
8
8
8
8
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
8
0
0
0
15
8
0
% Q
% Arg:
8
0
0
0
8
22
43
0
50
0
8
8
8
29
50
% R
% Ser:
15
29
50
22
15
15
15
36
0
22
8
50
50
0
0
% S
% Thr:
0
15
8
29
0
0
0
8
8
0
0
8
8
8
8
% T
% Val:
15
8
8
0
22
0
0
0
0
0
15
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _