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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP4C
All Species:
25.15
Human Site:
Y42
Identified Species:
42.56
UniProt:
Q96CF2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CF2
NP_689497.1
233
26411
Y42
M
L
G
K
K
Q
E
Y
L
E
N
R
I
Q
R
Chimpanzee
Pan troglodytes
XP_528179
346
37934
Y155
M
L
G
K
K
Q
E
Y
L
E
N
R
I
Q
R
Rhesus Macaque
Macaca mulatta
XP_001093735
233
26393
Y42
M
L
G
K
K
Q
E
Y
L
E
N
R
I
Q
R
Dog
Lupus familis
XP_535115
236
26393
Y42
M
L
S
K
K
Q
E
Y
L
E
A
R
V
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7F7
232
26261
Y42
M
L
A
K
K
Q
E
Y
L
E
N
R
I
Q
R
Rat
Rattus norvegicus
Q569C1
232
26305
Y42
M
M
A
K
K
Q
E
Y
L
E
N
R
I
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507822
358
38284
V111
H
R
G
P
Q
S
Q
V
S
G
R
G
H
P
T
Chicken
Gallus gallus
Q5ZHP5
227
25137
F44
M
L
S
K
K
Q
E
F
L
E
K
K
I
E
Q
Frog
Xenopus laevis
Q6GNN8
227
25461
Y46
M
L
T
K
K
Q
E
Y
L
E
K
K
I
E
L
Zebra Danio
Brachydanio rerio
Q6IQ73
224
25158
E42
A
K
K
Q
D
F
L
E
K
K
I
D
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610462
226
25425
K42
K
Q
E
F
L
E
A
K
I
E
D
E
L
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZE4
219
24314
E43
L
L
K
K
A
G
A
E
V
E
K
A
K
E
Y
Baker's Yeast
Sacchar. cerevisiae
P39929
240
26969
N46
H
L
R
T
Q
I
T
N
Q
E
N
E
A
R
I
Red Bread Mold
Neurospora crassa
Q871Y8
228
24957
L42
L
Q
K
R
E
R
H
L
Q
N
Q
I
D
E
Q
Conservation
Percent
Protein Identity:
100
67
98.7
88.1
N.A.
86.6
87.1
N.A.
41.3
64.3
71.2
63.5
N.A.
49.3
N.A.
N.A.
N.A.
Protein Similarity:
100
67.3
99.5
91
N.A.
92.6
93.1
N.A.
50.8
79.4
83.2
79.8
N.A.
69
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
86.6
N.A.
6.6
60
66.6
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
20
86.6
80
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
34.1
32.1
Protein Similarity:
N.A.
N.A.
N.A.
53.2
57
57
P-Site Identity:
N.A.
N.A.
N.A.
20
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
8
0
15
0
0
0
8
8
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% D
% Glu:
0
0
8
0
8
8
58
15
0
79
0
15
0
36
0
% E
% Phe:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
29
0
0
8
0
0
0
8
0
8
0
0
0
% G
% His:
15
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
8
8
50
0
15
% I
% Lys:
8
8
22
65
58
0
0
8
8
8
22
15
8
0
0
% K
% Leu:
15
65
0
0
8
0
8
8
58
0
0
0
8
0
15
% L
% Met:
58
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
43
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
15
0
8
15
58
8
0
15
0
8
0
0
43
15
% Q
% Arg:
0
8
8
8
0
8
0
0
0
0
8
43
0
8
43
% R
% Ser:
0
0
15
0
0
8
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _