KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIFA
All Species:
6.97
Human Site:
S173
Identified Species:
19.17
UniProt:
Q96CG3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CG3
NP_443096.1
184
21445
S173
Y
S
L
C
S
S
Q
S
S
S
P
T
E
M
D
Chimpanzee
Pan troglodytes
XP_526660
184
21463
N173
Y
S
L
C
S
S
Q
N
S
S
P
T
E
M
D
Rhesus Macaque
Macaca mulatta
XP_001092116
185
21687
S174
Y
S
L
C
S
S
Q
S
S
F
P
T
E
M
D
Dog
Lupus familis
XP_545028
208
24207
N197
Y
S
S
C
F
T
Q
N
T
S
P
T
E
M
D
Cat
Felis silvestris
Mouse
Mus musculus
Q793I8
184
21542
R173
Y
S
S
Y
F
T
H
R
S
S
P
S
E
M
D
Rat
Rattus norvegicus
Q5XIB9
185
21530
R174
Y
S
S
Y
F
T
H
R
S
S
P
A
E
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506200
185
21856
T174
S
A
I
F
H
S
R
T
E
Y
P
I
E
I
D
Chicken
Gallus gallus
XP_420645
187
21815
G175
P
S
L
S
P
S
Q
G
K
S
P
I
E
I
D
Frog
Xenopus laevis
Q2MHQ9
178
20664
L168
P
I
P
E
C
G
T
L
N
A
V
E
I
D
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.2
77.8
N.A.
76.6
78.3
N.A.
66.4
54
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.3
84.1
N.A.
88
88.6
N.A.
81.6
72.1
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
66.6
N.A.
53.3
53.3
N.A.
26.6
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
66.6
60
N.A.
60
60
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
45
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
89
% D
% Glu:
0
0
0
12
0
0
0
0
12
0
0
12
89
0
12
% E
% Phe:
0
0
0
12
34
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
23
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
0
23
12
23
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
45
0
0
0
0
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% M
% Asn:
0
0
0
0
0
0
0
23
12
0
0
0
0
0
0
% N
% Pro:
23
0
12
0
12
0
0
0
0
0
89
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
56
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
23
0
0
0
0
0
0
0
% R
% Ser:
12
78
34
12
34
56
0
23
56
67
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
34
12
12
12
0
0
45
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
23
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _