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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAF2
All Species:
23.94
Human Site:
S146
Identified Species:
43.89
UniProt:
Q96CJ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CJ1
NP_060926.2
260
28792
S146
N
L
V
K
H
S
P
S
E
D
K
M
S
P
A
Chimpanzee
Pan troglodytes
XP_001165769
260
28768
S146
N
L
V
K
H
S
P
S
E
D
K
M
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001111637
260
28705
S146
N
L
V
K
H
S
P
S
E
D
K
M
S
P
A
Dog
Lupus familis
XP_850700
250
27648
T137
Q
M
R
N
S
A
R
T
P
N
L
M
K
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD6
262
29169
S146
N
L
V
Q
H
S
P
S
E
E
K
M
S
P
T
Rat
Rattus norvegicus
Q811X5
262
28914
S146
N
L
V
Q
H
S
P
S
E
D
K
L
S
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514534
254
27236
A140
R
A
P
T
K
P
V
A
G
P
K
T
S
P
L
Chicken
Gallus gallus
Q5ZHP7
264
28989
F150
S
P
P
K
D
K
M
F
P
S
S
P
M
D
D
Frog
Xenopus laevis
NP_001080524
250
27199
P137
M
R
N
A
S
K
T
P
N
S
A
K
N
S
S
Zebra Danio
Brachydanio rerio
NP_001002162
259
27913
T146
G
S
K
A
P
S
S
T
K
S
S
P
P
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JRJ1
504
54910
V153
A
A
P
V
A
V
P
V
P
G
Q
G
S
G
T
Honey Bee
Apis mellifera
XP_394906
317
33904
T199
S
P
V
Q
P
S
V
T
H
S
V
L
A
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787179
315
33670
S148
R
S
S
S
Q
A
S
S
K
S
S
P
N
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.3
76.9
N.A.
80.1
79.7
N.A.
51.9
73.8
67.6
66.1
N.A.
24.2
32.8
N.A.
37.1
Protein Similarity:
100
99.6
98
83.8
N.A.
87.7
86.6
N.A.
65.3
85.2
78.4
77.6
N.A.
36.1
47.3
N.A.
50.1
P-Site Identity:
100
100
100
6.6
N.A.
80
80
N.A.
20
6.6
0
6.6
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
40
N.A.
93.3
93.3
N.A.
26.6
13.3
13.3
20
N.A.
20
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
16
8
16
0
8
0
0
8
0
8
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
31
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
39
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
8
0
8
0
8
0
% G
% His:
0
0
0
0
39
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
31
8
16
0
0
16
0
47
8
8
8
0
% K
% Leu:
0
39
0
0
0
0
0
0
0
0
8
16
0
0
16
% L
% Met:
8
8
0
0
0
0
8
0
0
0
0
39
8
0
0
% M
% Asn:
39
0
8
8
0
0
0
0
8
8
0
0
16
0
0
% N
% Pro:
0
16
24
0
16
8
47
8
24
8
0
24
8
54
0
% P
% Gln:
8
0
0
24
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
16
8
8
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
16
16
8
8
16
54
16
47
0
39
24
0
54
16
16
% S
% Thr:
0
0
0
8
0
0
8
24
0
0
0
8
0
0
24
% T
% Val:
0
0
47
8
0
8
16
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _