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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAF2
All Species:
18.18
Human Site:
S178
Identified Species:
33.33
UniProt:
Q96CJ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CJ1
NP_060926.2
260
28792
S178
D
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
Chimpanzee
Pan troglodytes
XP_001165769
260
28768
S178
D
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001111637
260
28705
S178
D
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
Dog
Lupus familis
XP_850700
250
27648
L169
E
L
K
A
E
A
S
L
M
D
Q
M
S
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD6
262
29169
S178
D
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
Rat
Rattus norvegicus
Q811X5
262
28914
S178
D
Q
M
S
S
C
D
S
S
S
D
S
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514534
254
27236
E172
R
A
E
V
E
I
I
E
Q
M
S
S
S
S
G
Chicken
Gallus gallus
Q5ZHP7
264
28989
K182
S
D
S
S
S
D
S
K
S
S
S
S
S
S
S
Frog
Xenopus laevis
NP_001080524
250
27199
V169
E
L
M
A
E
A
S
V
I
D
Q
M
S
S
S
Zebra Danio
Brachydanio rerio
NP_001002162
259
27913
M178
E
A
R
V
M
D
Q
M
S
S
G
D
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JRJ1
504
54910
N185
S
T
G
S
R
R
N
N
I
I
D
F
K
P
R
Honey Bee
Apis mellifera
XP_394906
317
33904
P231
F
P
V
T
N
S
I
P
S
R
S
S
C
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787179
315
33670
D180
S
Q
G
N
K
K
K
D
T
P
L
N
S
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.3
76.9
N.A.
80.1
79.7
N.A.
51.9
73.8
67.6
66.1
N.A.
24.2
32.8
N.A.
37.1
Protein Similarity:
100
99.6
98
83.8
N.A.
87.7
86.6
N.A.
65.3
85.2
78.4
77.6
N.A.
36.1
47.3
N.A.
50.1
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
13.3
46.6
20
26.6
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
13.3
46.6
33.3
33.3
N.A.
33.3
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
16
0
16
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
39
0
0
0
0
0
0
8
0
8
% C
% Asp:
39
8
0
0
0
16
39
8
0
16
47
8
0
0
0
% D
% Glu:
24
0
8
0
24
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
16
0
16
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
8
8
8
0
0
0
0
39
0
0
% K
% Leu:
0
16
0
0
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
47
0
8
0
0
8
8
8
0
16
0
0
0
% M
% Asn:
0
0
0
8
8
0
8
8
0
0
0
8
0
0
8
% N
% Pro:
0
8
0
0
0
0
0
8
0
8
0
0
0
16
0
% P
% Gln:
0
47
0
0
0
0
8
0
8
0
16
0
0
0
0
% Q
% Arg:
8
0
8
0
8
8
0
0
0
8
0
0
8
0
8
% R
% Ser:
24
0
8
54
47
8
24
39
62
54
24
62
47
77
62
% S
% Thr:
0
8
0
8
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
8
16
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _