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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAF2
All Species:
27.27
Human Site:
T112
Identified Species:
50
UniProt:
Q96CJ1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CJ1
NP_060926.2
260
28792
T112
S
N
I
T
V
K
K
T
R
V
E
G
S
S
K
Chimpanzee
Pan troglodytes
XP_001165769
260
28768
T112
S
N
I
T
V
K
K
T
R
V
E
G
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001111637
260
28705
T112
S
N
I
T
V
K
K
T
R
V
E
G
S
S
K
Dog
Lupus familis
XP_850700
250
27648
L103
G
E
C
R
L
E
K
L
S
S
N
I
T
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD6
262
29169
T112
S
N
I
T
V
K
K
T
R
V
E
G
S
S
R
Rat
Rattus norvegicus
Q811X5
262
28914
T112
S
N
I
T
V
K
K
T
R
G
E
G
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514534
254
27236
T106
S
S
I
H
V
K
K
T
R
A
E
G
S
S
K
Chicken
Gallus gallus
Q5ZHP7
264
28989
S116
K
K
I
R
A
E
G
S
S
K
V
Q
S
R
I
Frog
Xenopus laevis
NP_001080524
250
27199
S103
E
C
R
L
E
K
L
S
S
N
I
S
V
K
K
Zebra Danio
Brachydanio rerio
NP_001002162
259
27913
R112
N
I
A
V
K
K
T
R
A
E
G
S
S
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JRJ1
504
54910
T119
H
N
I
Q
V
K
K
T
R
N
E
V
T
N
K
Honey Bee
Apis mellifera
XP_394906
317
33904
Q165
K
K
R
E
P
S
I
Q
L
H
P
K
Q
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787179
315
33670
L114
C
N
I
Q
V
K
R
L
R
Q
E
G
T
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.3
76.9
N.A.
80.1
79.7
N.A.
51.9
73.8
67.6
66.1
N.A.
24.2
32.8
N.A.
37.1
Protein Similarity:
100
99.6
98
83.8
N.A.
87.7
86.6
N.A.
65.3
85.2
78.4
77.6
N.A.
36.1
47.3
N.A.
50.1
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
80
13.3
13.3
13.3
N.A.
60
0
N.A.
60
P-Site Similarity:
100
100
100
33.3
N.A.
100
93.3
N.A.
86.6
26.6
20
20
N.A.
73.3
0
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
8
16
0
0
0
8
62
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
8
8
54
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
70
0
0
0
8
0
0
0
8
8
0
0
16
% I
% Lys:
16
16
0
0
8
77
62
0
0
8
0
8
0
16
70
% K
% Leu:
0
0
0
8
8
0
8
16
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
54
0
0
0
0
0
0
0
16
8
0
0
8
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
8
0
8
0
8
8
0
0
% Q
% Arg:
0
0
16
16
0
0
8
8
62
0
0
0
0
8
8
% R
% Ser:
47
8
0
0
0
8
0
16
24
8
0
16
62
54
8
% S
% Thr:
0
0
0
39
0
0
8
54
0
0
0
0
24
0
0
% T
% Val:
0
0
0
8
62
0
0
0
0
31
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _