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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAF2
All Species:
10.61
Human Site:
Y222
Identified Species:
19.44
UniProt:
Q96CJ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CJ1
NP_060926.2
260
28792
Y222
G
H
P
T
M
T
Q
Y
R
I
P
D
I
D
A
Chimpanzee
Pan troglodytes
XP_001165769
260
28768
Y222
G
H
P
T
M
T
Q
Y
R
I
P
D
I
N
A
Rhesus Macaque
Macaca mulatta
XP_001111637
260
28705
Y222
G
H
P
T
M
A
Q
Y
R
I
P
D
I
D
A
Dog
Lupus familis
XP_850700
250
27648
V213
P
S
D
P
G
N
Y
V
S
G
H
P
A
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZD6
262
29169
P222
H
P
S
M
S
A
G
P
Q
Y
R
T
S
E
A
Rat
Rattus norvegicus
Q811X5
262
28914
P222
H
P
S
V
S
A
G
P
Q
Y
R
T
S
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514534
254
27236
S216
S
H
P
S
H
P
Q
S
N
N
R
S
S
V
A
Chicken
Gallus gallus
Q5ZHP7
264
28989
Q226
T
L
S
A
I
P
H
Q
A
V
P
D
K
D
A
Frog
Xenopus laevis
NP_001080524
250
27199
H213
K
Q
I
L
Q
R
H
H
S
G
S
S
T
E
S
Zebra Danio
Brachydanio rerio
NP_001002162
259
27913
S222
P
P
A
P
P
Q
S
S
S
A
L
S
I
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JRJ1
504
54910
I229
A
Q
Q
T
L
P
S
I
P
L
I
T
D
D
D
Honey Bee
Apis mellifera
XP_394906
317
33904
E275
S
D
S
D
S
D
T
E
N
I
P
V
L
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787179
315
33670
E224
V
P
S
V
V
D
R
E
A
D
S
S
D
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.3
76.9
N.A.
80.1
79.7
N.A.
51.9
73.8
67.6
66.1
N.A.
24.2
32.8
N.A.
37.1
Protein Similarity:
100
99.6
98
83.8
N.A.
87.7
86.6
N.A.
65.3
85.2
78.4
77.6
N.A.
36.1
47.3
N.A.
50.1
P-Site Identity:
100
93.3
93.3
0
N.A.
6.6
13.3
N.A.
26.6
26.6
0
6.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
93.3
6.6
N.A.
20
20
N.A.
33.3
40
20
6.6
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
24
0
0
16
8
0
0
8
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
16
0
0
0
8
0
31
16
39
8
% D
% Glu:
0
0
0
0
0
0
0
16
0
0
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
8
0
16
0
0
16
0
0
0
0
8
% G
% His:
16
31
0
0
8
0
16
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
8
0
31
8
0
31
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
0
8
8
0
0
0
0
8
8
0
8
0
0
% L
% Met:
0
0
0
8
24
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
16
8
0
0
0
8
0
% N
% Pro:
16
31
31
16
8
24
0
16
8
0
39
8
0
0
0
% P
% Gln:
0
16
8
0
8
8
31
8
16
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
8
0
24
0
24
0
0
0
0
% R
% Ser:
16
8
39
8
24
0
16
16
24
0
16
31
24
16
16
% S
% Thr:
8
0
0
31
0
16
8
0
0
0
0
24
8
8
0
% T
% Val:
8
0
0
16
8
0
0
8
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
24
0
16
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _