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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSF2
All Species:
18.18
Human Site:
T73
Identified Species:
50
UniProt:
Q96CM8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CM8
NP_079425.3
615
68125
T73
K
K
H
L
N
S
K
T
V
G
Q
C
L
E
T
Chimpanzee
Pan troglodytes
XP_001169992
615
68136
T73
K
K
H
L
N
S
K
T
V
G
Q
C
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001097818
618
68291
T76
K
N
H
L
L
S
K
T
V
G
R
C
L
E
A
Dog
Lupus familis
XP_537673
652
71902
T110
R
H
S
L
I
H
K
T
V
G
Q
C
L
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCW8
615
67932
T73
D
S
H
L
V
N
T
T
V
G
E
C
L
D
A
Rat
Rattus norvegicus
Q499N5
615
67868
T73
D
S
H
L
V
N
K
T
V
G
E
C
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420105
593
65617
R73
R
D
A
F
V
F
Y
R
D
G
V
R
K
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q0P4F7
606
67496
Q73
S
T
V
D
Q
C
L
Q
A
T
V
E
R
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S725
556
60824
T65
G
P
T
G
E
V
Y
T
Y
A
D
V
H
V
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.3
77.3
N.A.
78.6
79.8
N.A.
N.A.
60.4
N.A.
54.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
96.5
85.5
N.A.
88.1
88.9
N.A.
N.A.
76.7
N.A.
72.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
60
N.A.
46.6
53.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
66.6
N.A.
66.6
73.3
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
45
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
67
0
0
0
% C
% Asp:
23
12
0
12
0
0
0
0
12
0
12
0
0
23
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
23
12
0
45
0
% E
% Phe:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
12
% F
% Gly:
12
0
0
12
0
0
0
0
0
78
0
0
0
0
0
% G
% His:
0
12
56
0
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
23
0
0
0
0
56
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
67
12
0
12
0
0
0
0
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
23
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
12
0
0
12
0
0
34
0
0
0
0
% Q
% Arg:
23
0
0
0
0
0
0
12
0
0
12
12
12
0
0
% R
% Ser:
12
23
12
0
0
34
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
12
12
0
0
0
12
78
0
12
0
0
0
12
34
% T
% Val:
0
0
12
0
34
12
0
0
67
0
23
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
23
0
12
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _