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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVI5L
All Species:
16.36
Human Site:
S493
Identified Species:
36
UniProt:
Q96CN4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CN4
NP_660288.1
794
91376
S493
L
D
M
E
K
R
N
S
S
L
P
D
E
N
N
Chimpanzee
Pan troglodytes
XP_001153632
859
98748
N545
L
D
I
E
K
R
N
N
S
L
P
D
E
N
N
Rhesus Macaque
Macaca mulatta
XP_001093349
795
91203
S494
P
L
S
P
Q
R
N
S
S
L
P
D
E
N
N
Dog
Lupus familis
XP_542119
798
91683
S493
L
D
M
E
K
R
N
S
S
L
P
D
E
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P97366
809
92924
A558
K
D
P
P
K
K
N
A
V
N
E
L
Q
D
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512280
425
49637
E195
M
Q
D
Y
R
L
R
E
L
F
K
P
S
M
A
Chicken
Gallus gallus
XP_422340
823
95116
S512
L
E
M
E
K
R
N
S
S
L
P
D
E
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694682
828
94697
S524
L
D
L
E
K
R
N
S
S
L
P
D
E
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY9
807
92764
R531
E
E
D
K
K
T
L
R
E
T
T
P
D
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510667
435
50299
P205
G
L
L
L
L
Q
M
P
E
E
E
A
F
A
V
Sea Urchin
Strong. purpuratus
XP_799050
880
100294
N614
R
E
L
R
E
K
V
N
D
L
E
S
H
W
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
96.4
98.2
N.A.
63
N.A.
N.A.
43.5
66.9
N.A.
69.6
N.A.
36.6
N.A.
28.3
41.7
Protein Similarity:
100
76.9
97.4
99.1
N.A.
75.5
N.A.
N.A.
49.6
79.5
N.A.
80.6
N.A.
55.5
N.A.
39.9
59.6
P-Site Identity:
100
86.6
66.6
100
N.A.
20
N.A.
N.A.
0
86.6
N.A.
86.6
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
100
73.3
100
N.A.
46.6
N.A.
N.A.
13.3
93.3
N.A.
93.3
N.A.
40
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
19
0
0
0
0
0
10
0
0
55
10
10
0
% D
% Glu:
10
28
0
46
10
0
0
10
19
10
28
0
55
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
10
64
19
0
0
0
0
10
0
0
0
0
% K
% Leu:
46
19
28
10
10
10
10
0
10
64
0
10
0
0
0
% L
% Met:
10
0
28
0
0
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
64
19
0
10
0
0
0
46
55
% N
% Pro:
10
0
10
19
0
0
0
10
0
0
55
19
0
0
0
% P
% Gln:
0
10
0
0
10
10
0
0
0
0
0
0
10
0
10
% Q
% Arg:
10
0
0
10
10
55
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
46
55
0
0
10
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _