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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVI5L
All Species:
9.09
Human Site:
T259
Identified Species:
20
UniProt:
Q96CN4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CN4
NP_660288.1
794
91376
T259
E
Q
L
P
D
L
N
T
H
F
R
S
Q
S
F
Chimpanzee
Pan troglodytes
XP_001153632
859
98748
V307
E
H
L
P
E
L
F
V
H
F
Q
S
Q
S
F
Rhesus Macaque
Macaca mulatta
XP_001093349
795
91203
T259
E
Q
L
P
D
L
N
T
H
F
R
S
Q
S
F
Dog
Lupus familis
XP_542119
798
91683
T259
E
Q
L
P
D
L
N
T
H
F
R
S
Q
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P97366
809
92924
V307
E
Y
L
P
E
L
F
V
H
F
Q
S
Q
S
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512280
425
49637
Chicken
Gallus gallus
XP_422340
823
95116
V263
E
H
L
P
E
L
Y
V
H
F
Q
S
Q
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694682
828
94697
V294
E
Q
L
P
E
L
N
V
H
F
R
S
Q
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYY9
807
92764
I259
E
Q
I
P
D
M
H
I
H
F
Q
Q
Q
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510667
435
50299
Sea Urchin
Strong. purpuratus
XP_799050
880
100294
K383
D
L
L
P
D
L
F
K
H
F
T
A
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
96.4
98.2
N.A.
63
N.A.
N.A.
43.5
66.9
N.A.
69.6
N.A.
36.6
N.A.
28.3
41.7
Protein Similarity:
100
76.9
97.4
99.1
N.A.
75.5
N.A.
N.A.
49.6
79.5
N.A.
80.6
N.A.
55.5
N.A.
39.9
59.6
P-Site Identity:
100
66.6
100
100
N.A.
66.6
N.A.
N.A.
0
66.6
N.A.
86.6
N.A.
53.3
N.A.
0
53.3
P-Site Similarity:
100
80
100
100
N.A.
80
N.A.
N.A.
0
80
N.A.
93.3
N.A.
80
N.A.
0
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
73
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
28
0
0
82
0
0
0
0
82
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% G
% His:
0
19
0
0
0
0
10
0
82
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
10
73
0
0
73
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
37
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
46
0
0
0
0
0
0
0
0
37
10
82
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
64
0
64
0
% S
% Thr:
0
0
0
0
0
0
0
28
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _