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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EVI5L All Species: 33.03
Human Site: T386 Identified Species: 72.67
UniProt: Q96CN4 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CN4 NP_660288.1 794 91376 T386 I E I K R L R T E N R L L K Q
Chimpanzee Pan troglodytes XP_001153632 859 98748 T434 V E I K R L R T E N R L L K Q
Rhesus Macaque Macaca mulatta XP_001093349 795 91203 T386 I E I K R L R T E N R L L K Q
Dog Lupus familis XP_542119 798 91683 T386 I E I K R L R T E N R L L K Q
Cat Felis silvestris
Mouse Mus musculus P97366 809 92924 T434 G E I K R L R T E N R L L K Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512280 425 49637 L92 F R A I V W Q L L C S A Q S M
Chicken Gallus gallus XP_422340 823 95116 T390 V E I K R L R T E N R L L K Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694682 828 94697 T421 I E I K R L R T E N R L L K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYY9 807 92764 R386 A E L R R L R R E N C L L K Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_510667 435 50299 Y102 E V K K R P N Y I K D L V K R
Sea Urchin Strong. purpuratus XP_799050 880 100294 T510 I E M R R L R T E N R L L H Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.3 96.4 98.2 N.A. 63 N.A. N.A. 43.5 66.9 N.A. 69.6 N.A. 36.6 N.A. 28.3 41.7
Protein Similarity: 100 76.9 97.4 99.1 N.A. 75.5 N.A. N.A. 49.6 79.5 N.A. 80.6 N.A. 55.5 N.A. 39.9 59.6
P-Site Identity: 100 93.3 100 100 N.A. 93.3 N.A. N.A. 0 93.3 N.A. 100 N.A. 66.6 N.A. 26.6 80
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 6.6 100 N.A. 100 N.A. 80 N.A. 40 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 10 82 0 0 0 0 0 0 82 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 46 0 64 10 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 10 73 0 0 0 0 0 10 0 0 0 82 0 % K
% Leu: 0 0 10 0 0 82 0 10 10 0 0 91 82 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 10 0 0 82 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 82 % Q
% Arg: 0 10 0 19 91 0 82 10 0 0 73 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % T
% Val: 19 10 0 0 10 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _