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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC45
All Species:
16.36
Human Site:
S425
Identified Species:
40
UniProt:
Q96CN5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CN5
NP_659436.1
670
75951
S425
E
K
R
R
C
R
Q
S
L
E
D
S
E
S
L
Chimpanzee
Pan troglodytes
XP_511754
670
75932
S425
E
K
R
R
C
R
Q
S
L
E
D
S
E
S
L
Rhesus Macaque
Macaca mulatta
XP_001112894
670
75887
S425
E
K
R
R
C
R
Q
S
L
E
D
S
E
S
L
Dog
Lupus familis
XP_540494
670
75559
S425
E
K
K
R
S
R
Q
S
S
E
D
L
E
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM1
670
76392
N425
E
K
R
R
A
K
Q
N
M
E
D
L
E
K
L
Rat
Rattus norvegicus
NP_001121043
670
76290
N425
E
K
R
R
A
K
Q
N
M
E
D
L
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518502
480
52203
Q305
T
E
T
S
L
T
S
Q
G
P
E
K
R
G
D
Chicken
Gallus gallus
Q5ZI11
670
76049
S425
E
K
R
R
F
K
Q
S
L
E
D
M
E
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
L465
Y
R
E
K
F
I
R
L
Q
H
E
N
K
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185560
650
73855
D444
E
R
I
K
H
R
D
D
V
G
G
I
D
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.3
82.3
N.A.
84
84.3
N.A.
35.8
65.9
N.A.
20.7
N.A.
N.A.
N.A.
N.A.
40.3
Protein Similarity:
100
100
98.5
91.1
N.A.
92.6
92.6
N.A.
47.9
83.4
N.A.
40.7
N.A.
N.A.
N.A.
N.A.
61.7
P-Site Identity:
100
100
100
66.6
N.A.
60
60
N.A.
0
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
80
80
N.A.
13.3
86.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
0
70
0
10
0
10
% D
% Glu:
80
10
10
0
0
0
0
0
0
70
20
0
70
0
0
% E
% Phe:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
10
10
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
70
10
20
0
30
0
0
0
0
0
10
10
20
0
% K
% Leu:
0
0
0
0
10
0
0
10
40
0
0
30
0
0
80
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
20
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
70
10
10
0
0
0
0
10
0
% Q
% Arg:
0
20
60
70
0
50
10
0
0
0
0
0
10
10
10
% R
% Ser:
0
0
0
10
10
0
10
50
10
0
0
30
0
40
0
% S
% Thr:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _