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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISOC1
All Species:
22.73
Human Site:
S90
Identified Species:
50
UniProt:
Q96CN7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CN7
NP_057132.2
298
32237
S90
L
P
K
G
F
A
V
S
E
R
C
K
V
R
L
Chimpanzee
Pan troglodytes
XP_527000
289
31171
L83
E
W
G
Q
Y
V
D
L
P
K
G
F
A
V
S
Rhesus Macaque
Macaca mulatta
XP_001099145
298
32272
S90
L
P
K
G
F
A
V
S
E
R
C
K
V
R
L
Dog
Lupus familis
XP_850761
204
22220
L20
P
G
S
S
I
L
F
L
C
D
M
Q
E
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91V64
297
32014
S89
L
P
K
G
F
A
V
S
E
R
C
K
L
R
L
Rat
Rattus norvegicus
Q6I7R3
297
31984
S89
L
P
K
G
F
A
V
S
E
R
C
K
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413969
292
31709
S84
L
P
K
G
F
V
V
S
E
R
C
K
V
R
L
Frog
Xenopus laevis
Q5PQA5
306
33520
S98
L
P
K
G
F
I
I
S
E
R
C
K
I
R
L
Zebra Danio
Brachydanio rerio
Q08C33
283
31307
K77
K
G
F
T
V
S
E
K
C
R
L
R
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502315
199
21831
S15
A
R
I
N
P
T
N
S
A
L
F
V
C
D
L
Sea Urchin
Strong. purpuratus
XP_780645
199
21895
A15
G
N
I
S
P
E
T
A
A
L
F
V
C
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.9
35.9
N.A.
94.6
94.3
N.A.
N.A.
91.2
86.2
79.1
N.A.
N.A.
N.A.
36.9
43.9
Protein Similarity:
100
96.9
98.9
48.3
N.A.
97.3
96.9
N.A.
N.A.
95.3
92.1
89.5
N.A.
N.A.
N.A.
47.6
53.6
P-Site Identity:
100
0
100
0
N.A.
93.3
93.3
N.A.
N.A.
93.3
80
6.6
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
26.6
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
37
0
10
19
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
19
0
55
0
19
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
0
0
19
0
% D
% Glu:
10
0
0
0
0
10
10
0
55
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
55
0
10
0
0
0
19
10
0
0
10
% F
% Gly:
10
19
10
55
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
10
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
55
0
0
0
0
10
0
10
0
55
0
10
0
% K
% Leu:
55
0
0
0
0
10
0
19
0
19
10
0
28
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
55
0
0
19
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
64
0
10
0
55
0
% R
% Ser:
0
0
10
19
0
10
0
64
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
19
46
0
0
0
0
19
28
19
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _