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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISOC1
All Species:
32.42
Human Site:
T237
Identified Species:
71.33
UniProt:
Q96CN7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CN7
NP_057132.2
298
32237
T237
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Chimpanzee
Pan troglodytes
XP_527000
289
31171
T228
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Rhesus Macaque
Macaca mulatta
XP_001099145
298
32272
T237
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Dog
Lupus familis
XP_850761
204
22220
A155
A
R
M
R
Q
S
G
A
F
L
S
T
S
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91V64
297
32014
T236
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Rat
Rattus norvegicus
Q6I7R3
297
31984
T236
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413969
292
31709
T231
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Frog
Xenopus laevis
Q5PQA5
306
33520
T245
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Zebra Danio
Brachydanio rerio
Q08C33
283
31307
T222
V
H
I
V
A
D
A
T
S
S
R
S
M
M
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502315
199
21831
Q150
D
R
H
F
A
F
K
Q
M
E
Q
A
G
A
I
Sea Urchin
Strong. purpuratus
XP_780645
199
21895
Y150
M
M
D
R
Q
F
A
Y
E
R
L
R
Q
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.9
35.9
N.A.
94.6
94.3
N.A.
N.A.
91.2
86.2
79.1
N.A.
N.A.
N.A.
36.9
43.9
Protein Similarity:
100
96.9
98.9
48.3
N.A.
97.3
96.9
N.A.
N.A.
95.3
92.1
89.5
N.A.
N.A.
N.A.
47.6
53.6
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
82
0
82
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
73
0
0
0
0
0
0
0
0
73
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
19
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
19
% G
% His:
0
73
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% L
% Met:
10
10
10
0
0
0
0
0
10
0
0
0
73
73
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
0
10
0
0
10
0
10
0
0
% Q
% Arg:
0
19
0
19
0
0
0
0
0
10
73
10
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
73
73
10
73
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
73
0
0
0
10
0
0
0
% T
% Val:
73
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _