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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAF2
All Species:
31.52
Human Site:
S222
Identified Species:
57.78
UniProt:
Q96CS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CS3
NP_055428.1
445
52623
S222
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Chimpanzee
Pan troglodytes
XP_518117
512
60179
S289
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001090859
616
71241
S393
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Dog
Lupus familis
XP_546218
445
52633
S222
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3TDN2
445
52453
S222
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Rat
Rattus norvegicus
Q5BK32
346
41061
Y173
I
M
D
A
N
Q
T
Y
L
V
S
E
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517276
340
39675
G167
F
L
L
V
Y
L
H
G
D
D
H
Q
D
S
D
Chicken
Gallus gallus
Q5ZIA2
725
82295
L439
P
E
E
A
T
R
L
L
S
E
K
R
R
L
A
Frog
Xenopus laevis
Q6GQ69
445
52272
S222
K
P
E
G
F
R
V
S
Q
A
L
H
E
S
T
Zebra Danio
Brachydanio rerio
XP_002666842
443
52077
S222
K
P
E
G
Y
R
V
S
Q
A
L
R
E
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477388
464
52942
M233
T
P
E
G
Y
R
V
M
Q
S
I
T
V
R
S
Honey Bee
Apis mellifera
XP_395871
434
50570
A218
S
G
E
G
Y
K
V
A
E
A
L
K
S
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780136
438
51270
S216
S
P
E
G
Y
R
V
S
L
A
L
R
E
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
72
99.7
N.A.
97.7
76.6
N.A.
66.9
21.9
82.4
83.3
N.A.
43
46.7
N.A.
49.4
Protein Similarity:
100
86.9
72.2
100
N.A.
99.3
77.5
N.A.
71.2
35.7
92.8
93.9
N.A.
61.8
65.6
N.A.
68.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
6.6
20
80
100
N.A.
46.6
40
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
26.6
26.6
93.3
100
N.A.
66.6
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
8
0
70
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
8
0
0
8
0
8
% D
% Glu:
0
8
85
0
0
0
0
0
8
8
0
8
62
0
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
77
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
54
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
8
0
0
8
8
8
16
0
70
0
0
16
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
8
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
62
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
77
0
0
0
0
0
62
16
8
0
% R
% Ser:
16
0
0
0
0
0
0
62
8
8
8
0
8
16
16
% S
% Thr:
8
0
0
0
8
0
8
0
0
0
0
8
0
0
62
% T
% Val:
0
0
0
8
0
0
77
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
77
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _