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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAF2
All Species:
31.82
Human Site:
S381
Identified Species:
58.33
UniProt:
Q96CS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CS3
NP_055428.1
445
52623
S381
V
E
R
R
F
H
F
S
Q
S
L
T
V
I
H
Chimpanzee
Pan troglodytes
XP_518117
512
60179
S448
V
E
R
R
F
H
F
S
Q
S
L
T
V
I
H
Rhesus Macaque
Macaca mulatta
XP_001090859
616
71241
S552
V
E
R
R
F
H
F
S
Q
S
L
T
V
I
H
Dog
Lupus familis
XP_546218
445
52633
S381
V
E
R
R
F
H
F
S
Q
S
L
T
V
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3TDN2
445
52453
S381
V
E
R
R
F
H
F
S
Q
S
L
T
V
I
H
Rat
Rattus norvegicus
Q5BK32
346
41061
I288
F
S
Q
S
L
T
V
I
H
D
F
L
F
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517276
340
39675
D282
R
Q
G
D
G
V
L
D
S
Q
P
P
P
R
M
Chicken
Gallus gallus
Q5ZIA2
725
82295
N595
N
G
H
I
S
K
A
N
N
T
G
E
A
V
I
Frog
Xenopus laevis
Q6GQ69
445
52272
T381
V
E
R
R
F
L
F
T
Q
S
L
S
V
I
H
Zebra Danio
Brachydanio rerio
XP_002666842
443
52077
G379
V
E
R
R
F
L
F
G
Q
S
L
T
V
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477388
464
52942
T392
L
E
R
R
F
N
Q
T
D
S
V
L
D
V
Y
Honey Bee
Apis mellifera
XP_395871
434
50570
S376
M
K
R
R
F
L
M
S
D
T
V
E
D
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780136
438
51270
T375
L
E
R
S
F
L
K
T
C
S
L
E
V
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
72
99.7
N.A.
97.7
76.6
N.A.
66.9
21.9
82.4
83.3
N.A.
43
46.7
N.A.
49.4
Protein Similarity:
100
86.9
72.2
100
N.A.
99.3
77.5
N.A.
71.2
35.7
92.8
93.9
N.A.
61.8
65.6
N.A.
68.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
0
80
86.6
N.A.
33.3
26.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
20
93.3
86.6
N.A.
73.3
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
16
8
0
0
16
0
0
% D
% Glu:
0
70
0
0
0
0
0
0
0
0
0
24
0
0
0
% E
% Phe:
8
0
0
0
77
0
54
0
0
0
8
0
8
0
0
% F
% Gly:
0
8
8
0
8
0
0
8
0
0
8
0
0
0
0
% G
% His:
0
0
8
0
0
39
0
0
8
0
0
0
0
0
54
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
0
0
54
8
% I
% Lys:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
0
8
31
8
0
0
0
62
16
0
8
8
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
8
8
0
0
% P
% Gln:
0
8
8
0
0
0
8
0
54
8
0
0
0
0
0
% Q
% Arg:
8
0
77
70
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
16
8
0
0
47
8
70
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
24
0
16
0
47
0
0
0
% T
% Val:
54
0
0
0
0
8
8
0
0
0
16
0
62
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _