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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAF2
All Species:
30
Human Site:
S393
Identified Species:
55
UniProt:
Q96CS3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CS3
NP_055428.1
445
52623
S393
V
I
H
D
F
L
F
S
L
K
E
S
P
E
K
Chimpanzee
Pan troglodytes
XP_518117
512
60179
S460
V
I
H
D
F
L
F
S
L
K
E
S
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001090859
616
71241
S564
V
I
H
D
F
L
F
S
L
K
E
S
P
E
K
Dog
Lupus familis
XP_546218
445
52633
S393
V
I
H
D
F
L
F
S
L
K
E
S
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TDN2
445
52453
S393
V
I
H
D
F
L
F
S
L
K
E
S
P
E
K
Rat
Rattus norvegicus
Q5BK32
346
41061
E300
F
S
L
K
E
S
P
E
K
F
Q
I
E
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517276
340
39675
L294
P
R
M
V
P
Q
N
L
Q
E
E
K
E
R
K
Chicken
Gallus gallus
Q5ZIA2
725
82295
P607
A
V
I
T
S
P
A
P
P
M
E
P
S
G
G
Frog
Xenopus laevis
Q6GQ69
445
52272
S393
V
I
H
D
F
L
F
S
L
K
E
T
P
E
K
Zebra Danio
Brachydanio rerio
XP_002666842
443
52077
S391
V
I
H
D
F
L
F
S
L
K
E
T
P
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477388
464
52942
C404
D
V
Y
H
Y
L
F
C
H
P
D
S
P
D
E
Honey Bee
Apis mellifera
XP_395871
434
50570
S388
D
V
Y
Y
W
I
F
S
Q
P
D
S
P
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780136
438
51270
V387
V
L
Y
D
Y
V
Y
V
Q
D
E
V
P
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
72
99.7
N.A.
97.7
76.6
N.A.
66.9
21.9
82.4
83.3
N.A.
43
46.7
N.A.
49.4
Protein Similarity:
100
86.9
72.2
100
N.A.
99.3
77.5
N.A.
71.2
35.7
92.8
93.9
N.A.
61.8
65.6
N.A.
68.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
13.3
6.6
93.3
93.3
N.A.
26.6
26.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
20
13.3
100
100
N.A.
66.6
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
62
0
0
0
0
0
8
16
0
0
16
0
% D
% Glu:
0
0
0
0
8
0
0
8
0
8
77
0
16
54
16
% E
% Phe:
8
0
0
0
54
0
70
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
54
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
54
8
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
54
0
8
0
0
62
% K
% Leu:
0
8
8
0
0
62
0
8
54
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
8
8
8
8
8
16
0
8
77
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
24
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
0
8
8
0
62
0
0
0
54
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% T
% Val:
62
24
0
8
0
8
0
8
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
24
8
16
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _