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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAF2 All Species: 33.03
Human Site: S397 Identified Species: 60.56
UniProt: Q96CS3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CS3 NP_055428.1 445 52623 S397 F L F S L K E S P E K F Q I E
Chimpanzee Pan troglodytes XP_518117 512 60179 S464 F L F S L K E S P E K F Q I E
Rhesus Macaque Macaca mulatta XP_001090859 616 71241 S568 F L F S L K E S P E K F Q I E
Dog Lupus familis XP_546218 445 52633 S397 F L F S L K E S P E K F Q I E
Cat Felis silvestris
Mouse Mus musculus Q3TDN2 445 52453 S397 F L F S L K E S P E K F Q I E
Rat Rattus norvegicus Q5BK32 346 41061 I304 E S P E K F Q I E A N F P R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517276 340 39675 K298 P Q N L Q E E K E R K S E H L
Chicken Gallus gallus Q5ZIA2 725 82295 P611 S P A P P M E P S G G P Q L Q
Frog Xenopus laevis Q6GQ69 445 52272 T397 F L F S L K E T P E K F Q I V
Zebra Danio Brachydanio rerio XP_002666842 443 52077 T395 F L F S L K E T P E K F Q V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477388 464 52942 S408 Y L F C H P D S P D E F E I T
Honey Bee Apis mellifera XP_395871 434 50570 S392 W I F S Q P D S P V S F E I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780136 438 51270 V391 Y V Y V Q D E V P D E F Q L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 72 99.7 N.A. 97.7 76.6 N.A. 66.9 21.9 82.4 83.3 N.A. 43 46.7 N.A. 49.4
Protein Similarity: 100 86.9 72.2 100 N.A. 99.3 77.5 N.A. 71.2 35.7 92.8 93.9 N.A. 61.8 65.6 N.A. 68.7
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 13.3 13.3 86.6 80 N.A. 40 40 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 26.6 93.3 93.3 N.A. 73.3 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 16 0 0 16 0 0 0 0 0 % D
% Glu: 8 0 0 8 0 8 77 0 16 54 16 0 24 0 39 % E
% Phe: 54 0 70 0 0 8 0 0 0 0 0 85 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 0 0 62 0 % I
% Lys: 0 0 0 0 8 54 0 8 0 0 62 0 0 0 0 % K
% Leu: 0 62 0 8 54 0 0 0 0 0 0 0 0 16 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 8 8 8 8 16 0 8 77 0 0 8 8 0 0 % P
% Gln: 0 8 0 0 24 0 8 0 0 0 0 0 70 0 16 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % R
% Ser: 8 8 0 62 0 0 0 54 8 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 16 % T
% Val: 0 8 0 8 0 0 0 8 0 8 0 0 0 8 16 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _