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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAF2 All Species: 13.64
Human Site: S66 Identified Species: 25
UniProt: Q96CS3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CS3 NP_055428.1 445 52623 S66 S V F N P P P S R P L Q V N T
Chimpanzee Pan troglodytes XP_518117 512 60179 S133 S V F N P P P S R P L Q V N T
Rhesus Macaque Macaca mulatta XP_001090859 616 71241 S237 S V F N P P P S R P L Q V N T
Dog Lupus familis XP_546218 445 52633 S66 S V F N P P P S R P L Q V N T
Cat Felis silvestris
Mouse Mus musculus Q3TDN2 445 52453 A66 S V F N P P P A R P L Q V N T
Rat Rattus norvegicus Q5BK32 346 41061 F21 I F R F A L R F I R P D P R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517276 340 39675 E15 F Q D L T G I E S M D Q C R Q
Chicken Gallus gallus Q5ZIA2 725 82295 V171 T M N L S K H V D P V I N K R
Frog Xenopus laevis Q6GQ69 445 52272 N66 R V F N T T P N R P L Q V N T
Zebra Danio Brachydanio rerio XP_002666842 443 52077 A66 S V F N P P P A R P L Q V N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477388 464 52942 Q76 V L N D R F L Q Q V F S A N M
Honey Bee Apis mellifera XP_395871 434 50570 A62 E G R P S M Y A Q D S R S R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780136 438 51270 P60 T T Q A S Q P P V R T P E V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 72 99.7 N.A. 97.7 76.6 N.A. 66.9 21.9 82.4 83.3 N.A. 43 46.7 N.A. 49.4
Protein Similarity: 100 86.9 72.2 100 N.A. 99.3 77.5 N.A. 71.2 35.7 92.8 93.9 N.A. 61.8 65.6 N.A. 68.7
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. 6.6 6.6 73.3 93.3 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 6.6 26.6 80 100 N.A. 26.6 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 24 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 8 0 0 0 0 8 8 8 8 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % E
% Phe: 8 8 54 8 0 8 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 8 0 16 0 8 8 0 0 0 54 0 0 0 0 % L
% Met: 0 8 0 0 0 8 0 0 0 8 0 0 0 0 8 % M
% Asn: 0 0 16 54 0 0 0 8 0 0 0 0 8 62 8 % N
% Pro: 0 0 0 8 47 47 62 8 0 62 8 8 8 0 8 % P
% Gln: 0 8 8 0 0 8 0 8 16 0 0 62 0 0 8 % Q
% Arg: 8 0 16 0 8 0 8 0 54 16 0 8 0 24 8 % R
% Ser: 47 0 0 0 24 0 0 31 8 0 8 8 8 0 8 % S
% Thr: 16 8 0 0 16 8 0 0 0 0 8 0 0 0 54 % T
% Val: 8 54 0 0 0 0 0 8 8 8 8 0 54 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _