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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAF2 All Species: 32.73
Human Site: T425 Identified Species: 60
UniProt: Q96CS3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CS3 NP_055428.1 445 52623 T425 E E W P N P P T L Q E A G L S
Chimpanzee Pan troglodytes XP_518117 512 60179 T492 E E W P N P P T L Q E A G L S
Rhesus Macaque Macaca mulatta XP_001090859 616 71241 T596 E E W P N P P T L Q E A G L S
Dog Lupus familis XP_546218 445 52633 T425 E E W P N P P T L Q E A G L S
Cat Felis silvestris
Mouse Mus musculus Q3TDN2 445 52453 T425 E E W P N P P T L Q E A G L S
Rat Rattus norvegicus Q5BK32 346 41061 L327 E W P N P P T L Q E A G L S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517276 340 39675 F321 P E S V K I I F K L P N D S R
Chicken Gallus gallus Q5ZIA2 725 82295 M643 I V S H Q P P M N M D S N L N
Frog Xenopus laevis Q6GQ69 445 52272 T425 E E I P V P P T L Q E A G L S
Zebra Danio Brachydanio rerio XP_002666842 443 52077 T423 E D E P N P P T L M E A G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477388 464 52942 T445 A K E T L T K T L Q A V G L K
Honey Bee Apis mellifera XP_395871 434 50570 T415 Y P C R E I L T L S D V G L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780136 438 51270 S419 E E N E T V P S I G D A G L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 72 99.7 N.A. 97.7 76.6 N.A. 66.9 21.9 82.4 83.3 N.A. 43 46.7 N.A. 49.4
Protein Similarity: 100 86.9 72.2 100 N.A. 99.3 77.5 N.A. 71.2 35.7 92.8 93.9 N.A. 61.8 65.6 N.A. 68.7
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 20 86.6 80 N.A. 33.3 26.6 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 6.6 40 86.6 86.6 N.A. 40 40 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 16 62 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 24 0 8 0 0 % D
% Glu: 70 62 16 8 8 0 0 0 0 8 54 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 8 77 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 8 0 0 16 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 8 0 8 0 8 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 8 0 8 8 70 8 0 0 8 85 0 % L
% Met: 0 0 0 0 0 0 0 8 0 16 0 0 0 0 0 % M
% Asn: 0 0 8 8 47 0 0 0 8 0 0 8 8 0 8 % N
% Pro: 8 8 8 54 8 70 70 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 8 54 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 16 0 0 0 0 8 0 8 0 8 0 16 62 % S
% Thr: 0 0 0 8 8 8 8 70 0 0 0 0 0 0 8 % T
% Val: 0 8 0 8 8 8 0 0 0 0 0 16 0 0 0 % V
% Trp: 0 8 39 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _