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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAF2 All Species: 35.76
Human Site: Y176 Identified Species: 65.56
UniProt: Q96CS3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CS3 NP_055428.1 445 52623 Y176 E L R F L L V Y L H G D D H Q
Chimpanzee Pan troglodytes XP_518117 512 60179 Y243 E L R F L L V Y L H G D D H Q
Rhesus Macaque Macaca mulatta XP_001090859 616 71241 Y347 E L R F L L V Y L H G D D H Q
Dog Lupus familis XP_546218 445 52633 Y176 E L R F L L V Y L H G D D H Q
Cat Felis silvestris
Mouse Mus musculus Q3TDN2 445 52453 Y176 E L R F L L V Y L H G D D H Q
Rat Rattus norvegicus Q5BK32 346 41061 R127 Y R V S Q A L R E N T Y P F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517276 340 39675 V121 R S R V T D P V G D I V S F V
Chicken Gallus gallus Q5ZIA2 725 82295 E393 T G E S A N Q E E L A V Q A E
Frog Xenopus laevis Q6GQ69 445 52272 Y176 E L R F L L V Y L H G E D H Q
Zebra Danio Brachydanio rerio XP_002666842 443 52077 Y176 E L R Y L L V Y L H G E D H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477388 464 52942 H187 R F L I V Y L H K D P A K N P
Honey Bee Apis mellifera XP_395871 434 50570 Y172 E L R F L L V Y L H K D E A Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780136 438 51270 Y170 D L K F L L V Y L H G N D H Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 72 99.7 N.A. 97.7 76.6 N.A. 66.9 21.9 82.4 83.3 N.A. 43 46.7 N.A. 49.4
Protein Similarity: 100 86.9 72.2 100 N.A. 99.3 77.5 N.A. 71.2 35.7 92.8 93.9 N.A. 61.8 65.6 N.A. 68.7
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 0 93.3 86.6 N.A. 0 80 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 6.6 100 100 N.A. 26.6 86.6 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 0 0 8 8 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 0 16 0 47 62 0 0 % D
% Glu: 62 0 8 0 0 0 0 8 16 0 0 16 8 0 8 % E
% Phe: 0 8 0 62 0 0 0 0 0 0 0 0 0 16 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 0 62 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 70 0 0 0 62 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 8 0 8 0 0 % K
% Leu: 0 70 8 0 70 70 16 0 70 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 8 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 8 % P
% Gln: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 70 % Q
% Arg: 16 8 70 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 16 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % T
% Val: 0 0 8 8 8 0 70 8 0 0 0 16 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 8 0 70 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _