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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHB2
All Species:
6.67
Human Site:
Y146
Identified Species:
18.33
UniProt:
Q96CS7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CS7
NP_001094093.1
222
24736
Y146
A
P
E
Q
A
Y
G
Y
G
P
Y
G
G
A
Y
Chimpanzee
Pan troglodytes
XP_001145631
263
28941
Y187
A
P
E
Q
A
Y
G
Y
G
P
Y
G
G
A
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540978
221
24707
G146
T
P
E
T
Y
G
C
G
P
Y
S
G
A
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZC7
221
24555
G146
T
P
E
V
Y
G
Y
G
P
Y
S
G
A
Y
P
Rat
Rattus norvegicus
Q9WU68
223
25225
W146
C
K
V
E
R
R
I
W
V
R
V
Y
S
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520903
64
7776
Chicken
Gallus gallus
Q5F3S2
224
25391
G146
S
P
E
V
Y
G
Y
G
Y
G
Q
Y
H
G
A
Frog
Xenopus laevis
NP_001087159
217
24374
Y142
G
A
P
P
A
Y
G
Y
D
Q
Y
P
G
G
Y
Zebra Danio
Brachydanio rerio
NP_957296
223
24869
G146
P
Q
V
F
Y
P
D
G
Y
G
G
Y
V
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84
N.A.
91.4
N.A.
90
41.7
N.A.
24.7
78.1
62.1
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.4
N.A.
94.1
N.A.
95
56.9
N.A.
28.3
85.7
76.5
73.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
20
N.A.
20
6.6
N.A.
0
13.3
46.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
20
20
N.A.
0
20
46.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
0
0
34
0
0
0
0
0
0
0
23
23
12
% A
% Cys:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
56
12
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
34
34
45
23
23
12
45
34
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
56
12
12
0
12
0
0
23
23
0
12
0
23
23
% P
% Gln:
0
12
0
23
0
0
0
0
0
12
12
0
0
0
0
% Q
% Arg:
0
0
0
0
12
12
0
0
0
12
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
0
0
0
23
0
12
0
0
% S
% Thr:
23
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
23
23
0
0
0
0
12
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
45
34
23
34
23
23
34
34
0
23
45
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _