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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6OS All Species: 18.48
Human Site: S107 Identified Species: 33.89
UniProt: Q96CW6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CW6 NP_115554.1 309 35086 S107 E G R Y R V L S S R R S L G T
Chimpanzee Pan troglodytes XP_511054 165 19324
Rhesus Macaque Macaca mulatta XP_001091334 216 24947 F21 G G H T E T H F R F S H R G A
Dog Lupus familis XP_853763 311 35399 S108 E G R Y R V I S S R R S S G I
Cat Felis silvestris
Mouse Mus musculus Q7TPE5 306 35022 Y104 E V R K E G R Y R V V S S H R
Rat Rattus norvegicus NP_647544 305 35013 S107 E G R Y R V V S S H R S S G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505580 355 39940 S125 E R R Y R L V S Q R R P Y C V
Chicken Gallus gallus XP_413987 328 36922 A105 E N R Y R V V A S H R P G S S
Frog Xenopus laevis A2BDB7 313 36408 S105 V S R Y R I I S S H R P N S E
Zebra Danio Brachydanio rerio Q5U3I2 326 37021 S118 E E R Y R I L S S H R A G L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496943 251 27938 L56 N G A R V L D L P T Q E H G M
Sea Urchin Strong. purpuratus XP_001191447 325 35365 S124 K S K S K S K S K S D T K S K
Poplar Tree Populus trichocarpa XP_002325660 352 40266 W137 D A R F E Q I W R S R R G D K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.1 57.2 80.3 N.A. 76.3 76.6 N.A. 41.1 47.5 44.4 43.8 N.A. N.A. N.A. 22.6 21.8
Protein Similarity: 100 53.4 62.4 87.1 N.A. 83.5 84.1 N.A. 57.1 64.6 59.7 60.1 N.A. N.A. N.A. 40.4 38.1
P-Site Identity: 100 0 13.3 80 N.A. 20 80 N.A. 46.6 46.6 40 53.3 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 0 13.3 86.6 N.A. 20 86.6 N.A. 60 66.6 53.3 66.6 N.A. N.A. N.A. 26.6 33.3
Percent
Protein Identity: 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 8 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 0 8 0 0 8 0 % D
% Glu: 54 8 0 0 24 0 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 8 39 0 0 0 8 0 0 0 0 0 0 24 39 0 % G
% His: 0 0 8 0 0 0 8 0 0 31 0 8 8 8 0 % H
% Ile: 0 0 0 0 0 16 24 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 8 8 8 0 8 0 8 0 0 0 8 0 16 % K
% Leu: 0 0 0 0 0 16 16 8 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 24 0 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 0 % Q
% Arg: 0 8 70 8 54 0 8 0 24 24 62 8 8 0 8 % R
% Ser: 0 16 0 8 0 8 0 54 47 16 8 31 24 24 8 % S
% Thr: 0 0 0 8 0 8 0 0 0 8 0 8 0 0 16 % T
% Val: 8 8 0 0 8 31 24 0 0 8 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 54 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _