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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6OS All Species: 10.91
Human Site: S159 Identified Species: 20
UniProt: Q96CW6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CW6 NP_115554.1 309 35086 S159 S A G S C K T S D P D V I L C
Chimpanzee Pan troglodytes XP_511054 165 19324 V19 G T T S D P D V I L C N S V E
Rhesus Macaque Macaca mulatta XP_001091334 216 24947 V70 G Q T S D P D V I L C N S V E
Dog Lupus familis XP_853763 311 35399 S162 T G G S S K T S D P D V I L C
Cat Felis silvestris
Mouse Mus musculus Q7TPE5 306 35022 S156 A T D C R K T S D P D V I L C
Rat Rattus norvegicus NP_647544 305 35013 P157 D C R K T S D P D V I L C N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505580 355 39940 Q176 G P S S S Q D Q D Q E F Q V F
Chicken Gallus gallus XP_413987 328 36922 Q180 F T A A N A Q Q T G D P D V I
Frog Xenopus laevis A2BDB7 313 36408 M156 S P F Q L F D M V Q E E P E Q
Zebra Danio Brachydanio rerio Q5U3I2 326 37021 S175 V P G K M V V S D P E T I L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496943 251 27938 Q105 S L N G R L L Q P V T D G G G
Sea Urchin Strong. purpuratus XP_001191447 325 35365 G173 S S V S N G V G R N K G A T K
Poplar Tree Populus trichocarpa XP_002325660 352 40266 S187 E D Q K I L S S Y L P L L R E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.1 57.2 80.3 N.A. 76.3 76.6 N.A. 41.1 47.5 44.4 43.8 N.A. N.A. N.A. 22.6 21.8
Protein Similarity: 100 53.4 62.4 87.1 N.A. 83.5 84.1 N.A. 57.1 64.6 59.7 60.1 N.A. N.A. N.A. 40.4 38.1
P-Site Identity: 100 6.6 6.6 80 N.A. 66.6 6.6 N.A. 13.3 6.6 6.6 46.6 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 13.3 13.3 86.6 N.A. 73.3 13.3 N.A. 33.3 20 13.3 53.3 N.A. N.A. N.A. 6.6 20
Percent
Protein Identity: 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 8 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 8 0 8 8 0 0 0 0 0 16 0 8 0 31 % C
% Asp: 8 8 8 0 16 0 39 0 47 0 31 8 8 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 24 8 0 8 24 % E
% Phe: 8 0 8 0 0 8 0 0 0 0 0 8 0 0 8 % F
% Gly: 24 8 24 8 0 8 0 8 0 8 0 8 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 16 0 8 0 31 0 8 % I
% Lys: 0 0 0 24 0 24 0 0 0 0 8 0 0 0 8 % K
% Leu: 0 8 0 0 8 16 8 0 0 24 0 16 8 31 0 % L
% Met: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 16 0 0 0 0 8 0 16 0 8 0 % N
% Pro: 0 24 0 0 0 16 0 8 8 31 8 8 8 0 0 % P
% Gln: 0 8 8 8 0 8 8 24 0 16 0 0 8 0 8 % Q
% Arg: 0 0 8 0 16 0 0 0 8 0 0 0 0 8 0 % R
% Ser: 31 8 8 47 16 8 8 39 0 0 0 0 16 0 8 % S
% Thr: 8 24 16 0 8 0 24 0 8 0 8 8 0 8 0 % T
% Val: 8 0 8 0 0 8 16 16 8 16 0 24 0 31 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _