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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6OS All Species: 11.52
Human Site: S179 Identified Species: 21.11
UniProt: Q96CW6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CW6 NP_115554.1 309 35086 S179 I R E R L T V S E D G P G V R
Chimpanzee Pan troglodytes XP_511054 165 19324 P39 L T V S E D G P G V R R Q E E
Rhesus Macaque Macaca mulatta XP_001091334 216 24947 P90 L T V S E D G P G V R H Q E E
Dog Lupus familis XP_853763 311 35399 S182 I R E R L T V S E D G P R I G
Cat Felis silvestris
Mouse Mus musculus Q7TPE5 306 35022 S176 I R E R L T V S E D G S Q V N
Rat Rattus norvegicus NP_647544 305 35013 D177 E R L T V S E D G S Q V E H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505580 355 39940 G196 E T E D S E G G A A A F K I S
Chicken Gallus gallus XP_413987 328 36922 N200 E M I R E R L N V S E D H N K
Frog Xenopus laevis A2BDB7 313 36408 L176 D S E P E T I L C N S I K M I
Zebra Danio Brachydanio rerio Q5U3I2 326 37021 S195 I R E K L S V S G A G L G T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496943 251 27938 Y125 S D D V V Y D Y Y A I H E K R
Sea Urchin Strong. purpuratus XP_001191447 325 35365 E193 L F D A V I D E E A K S S S K
Poplar Tree Populus trichocarpa XP_002325660 352 40266 I207 V A E V E S D I H A Y L S N Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.1 57.2 80.3 N.A. 76.3 76.6 N.A. 41.1 47.5 44.4 43.8 N.A. N.A. N.A. 22.6 21.8
Protein Similarity: 100 53.4 62.4 87.1 N.A. 83.5 84.1 N.A. 57.1 64.6 59.7 60.1 N.A. N.A. N.A. 40.4 38.1
P-Site Identity: 100 0 0 80 N.A. 80 6.6 N.A. 6.6 6.6 13.3 53.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 6.6 6.6 86.6 N.A. 80 26.6 N.A. 13.3 26.6 33.3 66.6 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 8 39 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 16 8 0 16 24 8 0 24 0 8 0 0 0 % D
% Glu: 24 0 54 0 39 8 8 8 31 0 8 0 16 16 24 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 24 8 31 0 31 0 16 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 16 8 8 0 % H
% Ile: 31 0 8 0 0 8 8 8 0 0 8 8 0 16 8 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 8 0 16 8 16 % K
% Leu: 24 0 8 0 31 0 8 8 0 0 0 16 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 0 16 8 % N
% Pro: 0 0 0 8 0 0 0 16 0 0 0 16 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 24 0 16 % Q
% Arg: 0 39 0 31 0 8 0 0 0 0 16 8 8 0 16 % R
% Ser: 8 8 0 16 8 24 0 31 0 16 8 16 16 8 8 % S
% Thr: 0 24 0 8 0 31 0 0 0 0 0 0 0 8 0 % T
% Val: 8 0 16 16 24 0 31 0 8 16 0 8 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 8 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _