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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A6OS
All Species:
16.36
Human Site:
S273
Identified Species:
30
UniProt:
Q96CW6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CW6
NP_115554.1
309
35086
S273
R
G
S
A
D
Y
N
S
L
S
E
E
E
R
G
Chimpanzee
Pan troglodytes
XP_511054
165
19324
L130
G
S
A
D
Y
N
S
L
S
E
E
E
R
G
S
Rhesus Macaque
Macaca mulatta
XP_001091334
216
24947
L181
G
S
A
D
Y
N
S
L
S
E
E
E
R
G
S
Dog
Lupus familis
XP_853763
311
35399
S275
R
G
S
D
D
Y
D
S
F
S
E
E
E
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPE5
306
35022
S271
R
G
S
D
E
Y
N
S
L
S
E
E
E
R
S
Rat
Rattus norvegicus
NP_647544
305
35013
S270
R
G
S
D
E
Y
N
S
L
S
D
E
E
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505580
355
39940
L314
D
H
L
H
S
V
S
L
A
S
K
R
E
N
T
Chicken
Gallus gallus
XP_413987
328
36922
S293
E
E
K
D
S
E
E
S
S
S
D
E
D
Q
C
Frog
Xenopus laevis
A2BDB7
313
36408
Y278
E
E
R
Y
I
G
Y
Y
E
D
G
D
E
E
E
Zebra Danio
Brachydanio rerio
Q5U3I2
326
37021
S288
E
R
Y
G
G
C
W
S
E
E
H
S
Y
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496943
251
27938
E216
D
H
W
H
A
G
E
E
A
Y
S
D
E
S
F
Sea Urchin
Strong. purpuratus
XP_001191447
325
35365
D289
K
D
E
Y
R
Y
G
D
I
S
S
D
E
D
I
Poplar Tree
Populus trichocarpa
XP_002325660
352
40266
S305
S
E
A
S
L
D
E
S
E
R
E
E
E
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.1
57.2
80.3
N.A.
76.3
76.6
N.A.
41.1
47.5
44.4
43.8
N.A.
N.A.
N.A.
22.6
21.8
Protein Similarity:
100
53.4
62.4
87.1
N.A.
83.5
84.1
N.A.
57.1
64.6
59.7
60.1
N.A.
N.A.
N.A.
40.4
38.1
P-Site Identity:
100
13.3
13.3
80
N.A.
80
73.3
N.A.
13.3
20
6.6
6.6
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
26.6
26.6
86.6
N.A.
86.6
86.6
N.A.
26.6
40
13.3
6.6
N.A.
N.A.
N.A.
13.3
40
Percent
Protein Identity:
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
8
8
0
0
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
16
8
0
47
16
8
8
8
0
8
16
24
8
8
0
% D
% Glu:
24
24
8
0
16
8
24
8
24
24
47
62
70
16
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
16
31
0
8
8
16
8
0
0
0
8
0
0
16
16
% G
% His:
0
16
0
16
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
8
0
8
0
0
24
24
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
24
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
31
8
8
0
8
0
0
0
0
8
0
8
16
31
8
% R
% Ser:
8
16
31
8
16
0
24
54
24
54
16
8
0
16
31
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
16
16
39
8
8
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _