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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC7A6OS All Species: 20
Human Site: S79 Identified Species: 36.67
UniProt: Q96CW6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CW6 NP_115554.1 309 35086 S79 L R E V L R P S R D S Q Q R V
Chimpanzee Pan troglodytes XP_511054 165 19324
Rhesus Macaque Macaca mulatta XP_001091334 216 24947
Dog Lupus familis XP_853763 311 35399 S80 V R A A L R P S R G S Q Q R I
Cat Felis silvestris
Mouse Mus musculus Q7TPE5 306 35022 A76 I Q Q L V R A A L R P S R S S
Rat Rattus norvegicus NP_647544 305 35013 S79 V R A A L R P S R S S Q L R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505580 355 39940 S97 A A S L L R P S S G S K Q R I
Chicken Gallus gallus XP_413987 328 36922 S77 A V Q S L R P S L G S T Q R V
Frog Xenopus laevis A2BDB7 313 36408 S77 S C L T L R P S S E S K Q R I
Zebra Danio Brachydanio rerio Q5U3I2 326 37021 S90 A H H A L R P S Q G S S Q R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496943 251 27938 K28 I L H T K R A K H G G N P L V
Sea Urchin Strong. purpuratus XP_001191447 325 35365 T96 P Q A K P K P T S T S T T T S
Poplar Tree Populus trichocarpa XP_002325660 352 40266 K109 E Q K R T I K K Y S K Q E Q I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.1 57.2 80.3 N.A. 76.3 76.6 N.A. 41.1 47.5 44.4 43.8 N.A. N.A. N.A. 22.6 21.8
Protein Similarity: 100 53.4 62.4 87.1 N.A. 83.5 84.1 N.A. 57.1 64.6 59.7 60.1 N.A. N.A. N.A. 40.4 38.1
P-Site Identity: 100 0 0 66.6 N.A. 6.6 60 N.A. 46.6 53.3 46.6 46.6 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 0 0 80 N.A. 53.3 73.3 N.A. 66.6 60 66.6 60 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 24 24 0 0 16 8 0 0 0 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 39 8 0 0 0 0 % G
% His: 0 8 16 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 8 0 0 0 0 0 0 0 0 47 % I
% Lys: 0 0 8 8 8 8 8 16 0 0 8 16 0 0 0 % K
% Leu: 8 8 8 16 54 0 0 0 16 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 0 0 0 8 0 62 0 0 0 8 0 8 0 0 % P
% Gln: 0 24 16 0 0 0 0 0 8 0 0 31 47 8 0 % Q
% Arg: 0 24 0 8 0 70 0 0 24 8 0 0 8 54 0 % R
% Ser: 8 0 8 8 0 0 0 54 24 16 62 16 0 8 16 % S
% Thr: 0 0 0 16 8 0 0 8 0 8 0 16 8 8 0 % T
% Val: 16 8 0 8 8 0 0 0 0 0 0 0 0 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _