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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A6OS
All Species:
22.12
Human Site:
S82
Identified Species:
40.56
UniProt:
Q96CW6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CW6
NP_115554.1
309
35086
S82
V
L
R
P
S
R
D
S
Q
Q
R
V
R
R
N
Chimpanzee
Pan troglodytes
XP_511054
165
19324
Rhesus Macaque
Macaca mulatta
XP_001091334
216
24947
Dog
Lupus familis
XP_853763
311
35399
S83
A
L
R
P
S
R
G
S
Q
Q
R
I
R
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPE5
306
35022
P79
L
V
R
A
A
L
R
P
S
R
S
S
Q
L
R
Rat
Rattus norvegicus
NP_647544
305
35013
S82
A
L
R
P
S
R
S
S
Q
L
R
I
R
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505580
355
39940
S100
L
L
R
P
S
S
G
S
K
Q
R
I
L
K
S
Chicken
Gallus gallus
XP_413987
328
36922
S80
S
L
R
P
S
L
G
S
T
Q
R
V
V
Q
D
Frog
Xenopus laevis
A2BDB7
313
36408
S80
T
L
R
P
S
S
E
S
K
Q
R
I
Q
E
E
Zebra Danio
Brachydanio rerio
Q5U3I2
326
37021
S93
A
L
R
P
S
Q
G
S
S
Q
R
I
I
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496943
251
27938
G31
T
K
R
A
K
H
G
G
N
P
L
V
F
T
L
Sea Urchin
Strong. purpuratus
XP_001191447
325
35365
S99
K
P
K
P
T
S
T
S
T
T
T
S
S
S
S
Poplar Tree
Populus trichocarpa
XP_002325660
352
40266
K112
R
T
I
K
K
Y
S
K
Q
E
Q
I
L
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.1
57.2
80.3
N.A.
76.3
76.6
N.A.
41.1
47.5
44.4
43.8
N.A.
N.A.
N.A.
22.6
21.8
Protein Similarity:
100
53.4
62.4
87.1
N.A.
83.5
84.1
N.A.
57.1
64.6
59.7
60.1
N.A.
N.A.
N.A.
40.4
38.1
P-Site Identity:
100
0
0
73.3
N.A.
6.6
66.6
N.A.
46.6
53.3
46.6
46.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
0
0
86.6
N.A.
40
80
N.A.
80
66.6
73.3
66.6
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
31
% D
% Glu:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
39
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
47
8
0
0
% I
% Lys:
8
8
8
8
16
0
0
8
16
0
0
0
0
8
0
% K
% Leu:
16
54
0
0
0
16
0
0
0
8
8
0
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
8
0
62
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
31
47
8
0
16
8
0
% Q
% Arg:
8
0
70
0
0
24
8
0
0
8
54
0
24
24
16
% R
% Ser:
8
0
0
0
54
24
16
62
16
0
8
16
8
16
16
% S
% Thr:
16
8
0
0
8
0
8
0
16
8
8
0
0
8
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
24
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _