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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A6OS
All Species:
15.76
Human Site:
T177
Identified Species:
28.89
UniProt:
Q96CW6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CW6
NP_115554.1
309
35086
T177
E
L
I
R
E
R
L
T
V
S
E
D
G
P
G
Chimpanzee
Pan troglodytes
XP_511054
165
19324
D37
E
R
L
T
V
S
E
D
G
P
G
V
R
R
Q
Rhesus Macaque
Macaca mulatta
XP_001091334
216
24947
D88
E
R
L
T
V
S
E
D
G
P
G
V
R
H
Q
Dog
Lupus familis
XP_853763
311
35399
T180
E
L
I
R
E
R
L
T
V
S
E
D
G
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPE5
306
35022
T174
E
L
I
R
E
R
L
T
V
S
E
D
G
S
Q
Rat
Rattus norvegicus
NP_647544
305
35013
S175
I
R
E
R
L
T
V
S
E
D
G
S
Q
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505580
355
39940
E194
H
E
E
T
E
D
S
E
G
G
A
A
A
F
K
Chicken
Gallus gallus
XP_413987
328
36922
R198
A
V
E
M
I
R
E
R
L
N
V
S
E
D
H
Frog
Xenopus laevis
A2BDB7
313
36408
T174
E
K
D
S
E
P
E
T
I
L
C
N
S
I
K
Zebra Danio
Brachydanio rerio
Q5U3I2
326
37021
S193
K
M
I
R
E
K
L
S
V
S
G
A
G
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496943
251
27938
Y123
G
S
S
D
D
V
V
Y
D
Y
Y
A
I
H
E
Sea Urchin
Strong. purpuratus
XP_001191447
325
35365
I191
F
S
L
F
D
A
V
I
D
E
E
A
K
S
S
Poplar Tree
Populus trichocarpa
XP_002325660
352
40266
S205
S
A
V
A
E
V
E
S
D
I
H
A
Y
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.1
57.2
80.3
N.A.
76.3
76.6
N.A.
41.1
47.5
44.4
43.8
N.A.
N.A.
N.A.
22.6
21.8
Protein Similarity:
100
53.4
62.4
87.1
N.A.
83.5
84.1
N.A.
57.1
64.6
59.7
60.1
N.A.
N.A.
N.A.
40.4
38.1
P-Site Identity:
100
6.6
6.6
93.3
N.A.
86.6
6.6
N.A.
6.6
6.6
20
53.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
86.6
20
N.A.
6.6
26.6
33.3
80
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
0
0
0
0
8
39
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
8
16
8
0
16
24
8
0
24
0
8
0
% D
% Glu:
47
8
24
0
54
0
39
8
8
8
31
0
8
0
16
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
0
24
8
31
0
31
0
16
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
16
8
% H
% Ile:
8
0
31
0
8
0
0
8
8
8
0
0
8
8
0
% I
% Lys:
8
8
0
0
0
8
0
0
0
0
0
0
8
0
16
% K
% Leu:
0
24
24
0
8
0
31
0
8
8
0
0
0
16
0
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
16
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
24
% Q
% Arg:
0
24
0
39
0
31
0
8
0
0
0
0
16
8
8
% R
% Ser:
8
16
8
8
0
16
8
24
0
31
0
16
8
16
16
% S
% Thr:
0
0
0
24
0
8
0
31
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
16
16
24
0
31
0
8
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _